RAB3GAP2 抗体 (AA 1-115)
Quick Overview for RAB3GAP2 抗体 (AA 1-115) (ABIN6719633)
抗原
See all RAB3GAP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-115
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原理
- Anti-RAB3GAP2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-RAB3GAP2 Antibody Picoband® (ABIN6719633). Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human RAB3GAP2 recombinant protein (Position: M1-Q115).
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亚型
- IgG
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anti-RAB3 GTPase Activating Protein Subunit 2 (Non-Catalytic) (RAB3GAP2) (AA 277-387), (Catalytic Subunit) antibody
RAB3GAP2 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-RAB3 GTPase Activating Protein Subunit 2 (Non-Catalytic) (RAB3GAP2) (Internal Region) antibodyRAB3GAP2 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-RAB3 GTPase Activating Protein Subunit 2 (Non-Catalytic) (RAB3GAP2) (AA 943-972), (C-Term) antibodyRAB3GAP2 适用: 人 WB 宿主: 兔 Polyclonal RB24125 unconjugated
anti-RAB3 GTPase Activating Protein Subunit 2 (Non-Catalytic) (RAB3GAP2) (Internal Region) antibodyRAB3GAP2 适用: 人, 小鼠, 大鼠, 猴 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-RAB3 GTPase Activating Protein Subunit 2 (Non-Catalytic) (RAB3GAP2) (AA 1-200) antibodyRAB3GAP2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-RAB3 GTPase Activating Protein Subunit 2 (Non-Catalytic) (RAB3GAP2) (AA 417-466) antibodyRAB3GAP2 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Borck, G., Wunram, H., Steiert, A., Volk, A. E., Korber, F., Roters, S., Herkenrath, P., Wollnik, B., Morris-Rosendahl, D. J., Kubisch, C. A homozygous RAB3GAP2 mutation causes Warburg Micro syndrome. Hum. Genet. 129: 45-50, 2011. 2. Handley, M. T., Morris-Rosendahl, D. J., Brown, S., Macdonald, F., Hardy, C., Bem, D., Carpanini, S. M., Borck, G., Martorell, L., Izzi, C., Faravelli, F., Accorsi, P., and 23 others. Mutation spectrum in RAB3GAP1, RAB3GAP2, and RAB18 and genotype-phenotype correlations in Warburg Micro syndrome and Martsolf syndrome. Hum. Mutat. 34: 686-696, 2013. -
说明
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Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- RAB3GAP2 (RAB3 GTPase Activating Protein Subunit 2 (Non-Catalytic) (RAB3GAP2))
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别名
- RAB3GAP2
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背景
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Synonyms: Rab3 GTPase-activating protein non-catalytic subunit, RGAP-iso, Rab3 GTPase-activating protein 150 kDa subunit, Rab3-GAP p150, Rab3-GAP150, Rab3-GAP regulatory subunit, RAB3GAP2, KIAA0839
Tissue Specificity: Ubiquitous.
Background: Rab3 GTPase-activating protein non-catalytic subunit is an enzyme that in humans is encoded by the RAB3GAP2 gene. It is mapped to 1q41. The protein encoded by this gene belongs to the RAB3 protein family, members of which are involved in regulated exocytosis of neurotransmitters and hormones. This protein forms the Rab3 GTPase-activating complex with RAB3GAP1, where it constitutes the regulatory subunit, whereas the latter functions as the catalytic subunit. This gene has the highest level of expression in the brain, consistent with it having a key role in neurodevelopment. Mutations in this gene are associated with Martsolf syndrome.
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分子量
- 156 kDa
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基因ID
- 25782
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UniProt
- Q9H2M9
抗原
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