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SDCBP 抗体 (AA 2-259)

This anti-SDCBP antibody is a 兔 多克隆 antibody detecting SDCBP in WB 和 ELISA. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN6719608
发货至: 中国

Quick Overview for SDCBP 抗体 (AA 2-259) (ABIN6719608)

抗原

See all SDCBP 抗体
SDCBP (Syndecan Binding Protein (Syntenin) (SDCBP))

适用

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人, 大鼠, 小鼠

宿主

  • 65
  • 12
  • 1

克隆类型

  • 57
  • 21
多克隆

标记

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This SDCBP antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

    • 10
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    AA 2-259

    原理

    Anti-Syntenin/SDCBP Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Syntenin/SDCBP Antibody Picoband® (ABIN6719608). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Syntenin/SDCBP recombinant protein (Position: S2-S259).

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL
    ELISA, 0.1-0.5 μg/mL
    1. Borrell-Pages, M., Fernandez-Larrea, J., Borroto, A., Rojo, F., Baselga, J., Arribas, J. The carboxy-terminal cysteine of the tetraspanin L6 antigen is required for its interaction with SITAC, a novel PDZ protein. Molec. Biol. Cell 11: 4217-4225, 2000. 2. Fernandez-Larrea, J., Merlos-Suarez, A., Urena, J. M., Baselga, J., Arribas, J. A role for a PDZ protein in the early secretory pathway for the targeting of proTGF-alpha to the cell surface. Molec. Cell 3: 423-433, 1999. 3. Geijsen, N., Uings, I. J., Pals, C., Armstrong, J., McKinnon, M., Raaijmakers, J. A. M., Lammers, J.-W. J., Koenderman, L., Coffer, P. J. Cytokine-specific transcriptional regulation through an IL-5R-alpha interacting protein. Science 293: 1136-1138, 2001.

    说明

    Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    SDCBP (Syndecan Binding Protein (Syntenin) (SDCBP))

    别名

    SDCBP

    背景

    Synonyms: Syntenin-1, Melanoma differentiation-associated protein 9, MDA-9, Pro-TGF-alpha cytoplasmic domain-interacting protein 18, TACIP18, Scaffold protein Pbp1, Syndecan-binding protein 1, SDCBP, MDA9, SYCL

    Tissue Specificity: Expressed in lung cancers, including adenocarcinoma, squamous cell carcinoma and small-cell carcinoma. Widely expressed. Expressed in fetal kidney, liver, lung and brain. In adult highest expression in heart and placenta.

    Background: Syntenin-1 is a protein that in humans is encoded by the SDCBP gene. It is mapped to 8q12.1. The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. Alternative splicing results in multiple transcript variants encoding different isoforms. Related pseudogenes have been identified on multiple chromosomes.

    分子量

    32 kDa

    基因ID

    6386

    UniProt

    O00560
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