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CCL8 抗体 (AA 24-97)

CCL8 适用: 小鼠, 大鼠 ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6719605
发货至: 中国
  • 抗原 See all CCL8 抗体
    CCL8 (Chemokine (C-C Motif) Ligand 8 (CCL8))
    抗原表位
    • 24
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 24-97
    适用
    • 43
    • 10
    • 2
    • 2
    • 1
    小鼠, 大鼠
    宿主
    • 44
    • 11
    • 1
    • 1
    克隆类型
    • 45
    • 12
    多克隆
    标记
    • 31
    • 9
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CCL8 antibody is un-conjugated
    应用范围
    • 32
    • 23
    • 14
    • 14
    • 12
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for CCL8 detection. Tested with IHC-P, ELISA(Cap) in Mouse,Rat.
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for CCL8 detection. Tested with IHC-P, ELISA(Cap) in Mouse,Rat.
    纯化方法
    Immunogen affinity purified.
    免疫原
    E. coli-derived mouse CCL8 recombinant protein (Position: G24-P97).
    亚型
    IgG
    Top Product
    Discover our top product CCL8 Primary Antibody
  • 应用备注

    Application details: Immunohistochemistry(Paraffin-embedded Section)|0.5-1 μg/mL ELISA(Cap)|1-5 μg/mL

    说明

    Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    缓冲液
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    CCL8 (Chemokine (C-C Motif) Ligand 8 (CCL8))
    别名
    Ccl8 (CCL8 产品)
    别名
    HC14 antibody, MCP-2 antibody, MCP2 antibody, SCYA10 antibody, SCYA8 antibody, 1810063B20Rik antibody, AB023418 antibody, Mcp2 antibody, Scya8 antibody, C-C motif chemokine ligand 8 antibody, chemokine (C-C motif) ligand 8 antibody, C-C motif chemokine 8 antibody, monocyte chemoattractant protein-2 precursor antibody, CCL8 antibody, Ccl8 antibody, LOC101119572 antibody, MCP-2 antibody
    背景

    Synonyms: C-C motif chemokine 8, Monocyte chemoattractant protein 2, Monocyte chemotactic protein 2, MCP-2, Small-inducible cytokine A8, Ccl8, Mcp2, Scya8

    Background: CCL8, also known as monocyte chemoattractant protein 2 (MCP2), is a protein that in humans is encoded by the CCL8 gene. It is a small cytokine belonging to the CC chemokine family. The CCL8 protein is produced as a precursor containing 109 amino acids, which is cleaved to produce mature CCL8 containing 75 amino acids. The gene for CCL8 is encoded by 3 exons and is located within a large cluster of CC chemokines on chromosome 17q11.2 in humans. MCP-2 is chemotactic for and activates many different immune cells, including mast cells, eosinophils and basophils, (that are implicated in allergic responses), and monocytes, T cells, and NK cells that are involved in the inflammatory response. CCL8 elicits its effects by binding to several different cell surface receptors called chemokine receptors. These receptors include CCR1, CCR2B, CCR3 and CCR5.

    基因ID
    20307
    UniProt
    Q9Z121
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