CCL8 抗体 (AA 24-97)
Quick Overview for CCL8 抗体 (AA 24-97) (ABIN6719605)
抗原
See all CCL8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 24-97
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原理
- Anti-CCL8 Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-CCL8 Antibody Picoband® (ABIN6719605). Tested in ELISA, IHC applications. This antibody reacts with Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived mouse CCL8 recombinant protein (Position: G24-P97).
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亚型
- IgG
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anti-Chemokine (C-C Motif) Ligand 8 (CCL8) (AA 24-99) antibody
CCL8 适用: 人 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 8 (CCL8) (AA 1-99) antibodyCCL8 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 8 (CCL8) (AA 20-94) antibodyCCL8 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 8 (CCL8) (AA 1-99) antibodyCCL8 适用: Cow WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 8 (CCL8) (AA 24-99) antibodyCCL8 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 8 (CCL8) (C-Term) antibodyCCL8 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 8 (CCL8) (AA 23-99) antibodyCCL8 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
ELISA (Cap), 1-5 μg/mL
1. GRCh38: Ensembl release 89: ENSG00000108700 - Ensembl, May 2017. 2. Proost P, Wuyts A, Van Damme J (January 1996). "Human monocyte chemotactic proteins-2 and -3: structural and functional comparison with MCP-1". J. Leukoc. Biol. 59 (1): 67-74. PMID 8558070. -
说明
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Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- CCL8 (Chemokine (C-C Motif) Ligand 8 (CCL8))
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别名
- Ccl8
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背景
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Synonyms: C-C motif chemokine 8, Monocyte chemoattractant protein 2, Monocyte chemotactic protein 2, MCP-2, Small-inducible cytokine A8, Ccl8, Mcp2, Scya8
Background: CCL8, also known as monocyte chemoattractant protein 2 (MCP2), is a protein that in humans is encoded by the CCL8 gene. It is a small cytokine belonging to the CC chemokine family. The CCL8 protein is produced as a precursor containing 109 amino acids, which is cleaved to produce mature CCL8 containing 75 amino acids. The gene for CCL8 is encoded by 3 exons and is located within a large cluster of CC chemokines on chromosome 17q11.2 in humans. MCP-2 is chemotactic for and activates many different immune cells, including mast cells, eosinophils and basophils, (that are implicated in allergic responses), and monocytes, T cells, and NK cells that are involved in the inflammatory response. CCL8 elicits its effects by binding to several different cell surface receptors called chemokine receptors. These receptors include CCR1, CCR2B, CCR3 and CCR5.
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分子量
- 71 kDa
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基因ID
- 20307
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UniProt
- Q9Z121
抗原
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