DIS3 抗体 (AA 62-304)
Quick Overview for DIS3 抗体 (AA 62-304) (ABIN6719579)
抗原
See all DIS3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 62-304
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原理
- Anti-DIS3 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-DIS3 Antibody (ABIN6719579). Tested in ELISA, Flow Cytometry, IP, IF, ICC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human DIS3 recombinant protein (Position: Q62-A304).
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亚型
- IgG
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anti-Exosome Complex Exonuclease RRP44 (DIS3) (AA 861-956) antibody
DIS3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2C7 unconjugated
anti-Exosome Complex Exonuclease RRP44 (DIS3) (AA 1-958) antibodyDIS3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Exosome Complex Exonuclease RRP44 (DIS3) (AA 861-956) antibodyDIS3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Exosome Complex Exonuclease RRP44 (DIS3) (AA 295-323) antibodyDIS3 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Exosome Complex Exonuclease RRP44 (DIS3) (AA 30-187) antibodyDIS3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Exosome Complex Exonuclease RRP44 (DIS3) (AA 290-339) antibodyDIS3 适用: 人, 小鼠, 大鼠, Cow, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Exosome Complex Exonuclease RRP44 (DIS3) (AA 1-280) antibodyDIS3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Exosome Complex Exonuclease RRP44 (DIS3) (AA 295-323) antibodyDIS3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB24091 unconjugated
anti-Exosome Complex Exonuclease RRP44 (DIS3) (AA 302-331), (Middle Region) antibodyDIS3 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
Immunocytochemistry/Immunofluorescence, 5 μg/mL
Immunoprecipitation, 0.5-2 μg/mL, Human
Flow Cytometry(Fixed), 1-3 μg/1x106 cells
ELISA, 0.1-0.5 μg/mL
1. Nagase, T., Ishikawa, K., Suyama, M., Kikuno, R., Hirosawa, M., Miyajima, N., Tanaka, A., Kotani, H., Nomura, N., Ohara, O. Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. DNA Res. 6: 63-70, 1999. 2. Rozenblum, E., Vahteristo, P., Sandberg, T., Bergthorsson, J. T., Syrjakoski, K., Weaver, D., Haraldsson, K., Johannsdottir, H. K., Vehmanen, P., Nigam, S., Golberger, N., Robbins, C., and 12 others. A genomic map of a 6-Mb region at 13q21-q22 implicated in cancer development: identification and characterization of candidate genes. Hum. Genet. 110: 111-121, 2002. 3. Tomecki, R., Kristiansen, M. S., Lykke-Andersen, S., Chlebowski, A., Larsen, K. M., Szczesny, R. J., Drazkowska, K., Pastula, A., Andersen, J. S., Stepien, P. P., Dziembowski, A., Jensen, T. H. The human core exosome interacts with differentially localized processive RNases: hDIS3 and hDIS3L. EMBO J. 29: 2342-2357, 2010. -
说明
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Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- DIS3 (Exosome Complex Exonuclease RRP44 (DIS3))
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别名
- DIS3
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背景
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Synonyms: Exosome complex exonuclease RRP44, Protein DIS3 homolog, Ribosomal RNA-processing protein 44, DIS3, KIAA1008, RRP44
Tissue Specificity: Widely expressed.
Background: Exosome complex exonuclease RRP44 or Dis3 is an enzyme that in humans is encoded by the DIS3 gene. Its protein product is an RNase enzyme homologous to the yeast protein Rrp44, and can be part of the exosome complex in the nucleus of eukaryotic cells. By genomic sequence analysis, this gene is mapped to chromosome 13q21-q22. Expression of human DIS3 could partially complement Dis3 depletion in yeast.
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分子量
- 109 kDa
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UniProt
- Q9Y2L1
抗原
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