GSTM1 抗体 (DyLight 550)
Quick Overview for GSTM1 抗体 (DyLight 550) (ABIN6719573)
抗原
See all GSTM1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Human GSTM1 DyLight® 550 conjugated Antibody(monoclonal, 11F2)
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序列
- EEEKIRVDIL ,ENQTMDNHMQ LGMICYNPEF EKLK
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Human GSTM1 DyLight® 550 conjugated Antibody (monoclonal, 11F2) (ABIN5693233)-Dyl550. Tested in Flow Cytometry applications. This antibody reacts with Human.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human GSTM1, which shares 70.6% and 73.5% amino acid (aa) sequence identity with mouse and rat GSTM1, respectively.
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亚型
- IgG1
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anti-Glutathione S-Transferase mu 1 (GSTM1) antibody
GSTM1 适用: 人, 猴 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 1H4A4 unconjugated
anti-Glutathione S-Transferase mu 1 (GSTM1) (AA 1-218) antibodyGSTM1 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Glutathione S-Transferase mu 1 (GSTM1) (AA 1-218) antibodyGSTM1 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Glutathione S-Transferase mu 1 (GSTM1) antibodyGSTM1 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal CPTC-GSTMu1-3 unconjugated
anti-Glutathione S-Transferase mu 1 (GSTM1) (AA 1-218) antibodyGSTM1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Glutathione S-Transferase mu 1 (GSTM1) (AA 24-156) antibodyGSTM1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutathione S-Transferase mu 1 (GSTM1) (AA 184-211), (C-Term) antibodyGSTM1 适用: 人, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB21078 unconjugated
anti-Glutathione S-Transferase mu 1 (GSTM1) (C-Term) antibodyGSTM1 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glutathione S-Transferase mu 1 (GSTM1) (AA 1-220) antibodyGSTM1 适用: 小鸡 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Glutathione S-Transferase mu 1 (GSTM1) (AA 31-80) antibodyGSTM1 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 豚鼠, 马, 猴, Bat, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow Cytometry (Fixed), 1-3 μg/1x106 cells1. Carless, M. A., Lea, R. A., Curran, J. E., Appleyard, B., Gaffney, P., Green, A., Griffiths, L. R. TheGSTM1 null genotype confers an increased risk for solar keratosis development in an Australian Caucasian population. J. Invest. Derm. 119: 1373-1378, 2002. 2. Zhong, S., Wyllie, A. H., Barnes, D., Wolf, C. R., Spurr, N. K. Relationship between theGSTM1 genetic polymorphism and susceptibility to bladder, breast and colon cancer.Carcinogenesis 14: 1821-1824, 1993.
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说明
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Other applications have not been tested. Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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- GSTM1 (Glutathione S-Transferase mu 1 (GSTM1))
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别名
- GSTM1
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背景
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Synonyms: Glutathione S-transferase Mu 1, GST HB subunit 4, GST class-mu 1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GSTM1, GST1
Tissue Specificity: Liver (at protein level).
Background: Glutathione S-transferase Mu 1 (gene name GSTM1) is a human glutathione S-transferase. Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene.
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分子量
- 39 kDa
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基因ID
- 2944
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UniProt
- P09488
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途径
- Negative Regulation of Transporter Activity
抗原
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