TMEM166 抗体
Quick Overview for TMEM166 抗体 (ABIN6719564)
抗原
See all TMEM166 (FAM176A) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Anti-TMEM166/EVA1A Antibody Picoband®
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序列
- MRLPLSHSPE HVEMALLSNI LAAYSFVSEN PERA
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-TM/EVA1A Antibody Picoband® (ABIN6719564). Tested in Flow Cytometry, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human TMEM166/EVA1A, which shares 66.7% and 50% amino acid (aa) sequence identity with mouse and rat TMEM166/EVA1A, respectively.
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亚型
- IgG
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anti-Family with Sequence Similarity 176, Member A (FAM176A) (AA 58-152) antibody
FAM176A 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Family with Sequence Similarity 176, Member A (FAM176A) (AA 104-137) antibodyFAM176A 适用: 斑马鱼 WB 宿主: 兔 Polyclonal RB51996 unconjugated
anti-Family with Sequence Similarity 176, Member A (FAM176A) (N-Term) antibodyFAM176A 适用: 人, 小鼠, 犬, 马, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Family with Sequence Similarity 176, Member A (FAM176A) (AA 51-100) antibodyFAM176A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Family with Sequence Similarity 176, Member A (FAM176A) (N-Term) antibodyFAM176A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Family with Sequence Similarity 176, Member A (FAM176A) (Middle Region) antibodyFAM176A 适用: 人, 犬, 马, 兔, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- 1. Sun W, Ma XM, Bai JP, Zhang GQ, Zhu YJ, Ma HM, Guo H, Chen YY, Ding JB (2012). "Transmembrane protein 166 expression in esophageal squamous cell carcinoma in Xinjiang, China". Asian Pacific Journal of Cancer Prevention. 13 (8): 3713-6. 2. Wang L, Yu C, Lu Y, He P, Guo J, Zhang C, Song Q, Ma D, Shi T, Chen Y (August 2007). "TMEM166, a novel transmembrane protein, regulates cell autophagy and apoptosis". Apoptosis. 12 (8): 1489-502.
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说明
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Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- TMEM166 (FAM176A) (Family with Sequence Similarity 176, Member A (FAM176A))
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别名
- EVA1A
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背景
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Synonyms: Protein eva-1 homolog A, Protein FAM176A, Transmembrane protein 166, EVA1A, FAM176A, TMEM166, SP24
Tissue Specificity: Expressed in lung, kidney, liver, pancreas, placenta, but not in heart and skeletal muscle.
Background: Eva-1 homolog A (C. elegans) is a protein that in humans is encoded by the EVA1A gene. It belongs to the FAM176 family. This gene is mapped to 2p12. EVA1A, also called TMEM166, acts as a regulator of programmed cell death, mediating both autophagy and apoptosis.
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分子量
- 21 kDa
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基因ID
- 84141
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UniProt
- Q9H8M9
抗原
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