Liver Arginase 抗体 (AA 25-183)
Quick Overview for Liver Arginase 抗体 (AA 25-183) (ABIN6719532)
抗原
See all Liver Arginase (ARG1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 25-183
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原理
- Anti-liver Arginase/ARG1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-liver Arginase/ARG1 Antibody Picoband® (ABIN6719532). Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human liver Arginase/ARG1 recombinant protein (Position: E25-D183).
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亚型
- IgG
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anti-Arginase, Liver (ARG1) antibody
KO Validated ARG1 适用: 人 WB, ELISA, FACS, IHC (p), IF, IP, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Arginase, Liver (ARG1) (C-Term) antibodyVerified ARG1 适用: 大鼠, 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Arginase, Liver (ARG1) (C-Term) antibodyVerified ARG1 适用: 人, 大鼠, 小鼠, Pig WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Arginase, Liver (ARG1) (AA 11-97) antibodyARG1 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal ARG1-1125 unconjugated
anti-Arginase, Liver (ARG1) (C-Term) antibodyARG1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Arginase, Liver (ARG1) (N-Term) antibodyARG1 适用: 人, 大鼠, 小鼠, Cow, 兔, 犬, Pig, 马, 山羊, 豚鼠, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Arginase, Liver (ARG1) (AA 293-322) antibodyARG1 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Arginase, Liver (ARG1) (AA 151-220) antibodyARG1 适用: 人, 大鼠 ELISA, FACS, IHC (p), ICC, IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Arginase, Liver (ARG1) (AA 1-322) antibodyARG1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Arginase, Liver (ARG1) (N-Term) antibodyARG1 适用: 人, 大鼠, 小鼠, Cow, 兔, 犬, Pig, 马, 猴, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Cardoso, M. L., Martins, E., Vasconcelos, R., Vilarinho, L., Rocha, J. Identification of a novel R21X mutation in the liver-type arginase gene (ARG1) in four Portuguese patients with argininemia. Hum. Mutat. 14: 355-356, 1999. 2. Grody, W. W., Dodson, A., Klein, D., Kern, R. M., Bassand, P., Cederbaum, S. D. Molecular genetic study of human arginase deficiency. (Abstract) Am. J. Hum. Genet. 45 (suppl.): A191 only, 1989. 3. Haraguchi, Y., Takiguchi, M., Amaya, Y., Kawamoto, S., Matsuda, I., Mori, M. Molecular cloning and nucleotide sequence of cDNA for human liver arginase. Proc. Nat. Acad. Sci. 84: 412-415, 1987. -
说明
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Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Liver Arginase (ARG1) (Arginase, Liver (ARG1))
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别名
- ARG1
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背景
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Synonyms: Arginase-1, Liver-type arginase, Type I arginase, ARG1
Tissue Specificity: Within the immune system initially reported to be selectively expressed in granulocytes (polymorphonuclear leukocytes [PMNs]). Also detected in macrophages mycobacterial granulomas. Expressed in group2 innate lymphoid cells (ILC2s) during lung disease.
Background: ARG1 (arginase, live) is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. The isoform encoded by ARG1, referred to as the liver, or A-I, isoform, contributes 98 % of the arginase activity in liver but is also present in red cells. Using a rat liver ARG1 cDNA clone to probe a human liver cDNA library, Haraguchi et al. (1987) isolated and characterized a cDNA corresponding to the ARG1 gene. The ARG1 gene is mapped on 6q23.2 and the arginase gene contains 8 exons. By immunologic studies, 90 % of the arginase in red blood cell and liver was precipitated by the antibody, whereas only 50 % of the arginase in kidney, brain, and the gastrointestinal tract reacted with it. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene.
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分子量
- 37 kDa
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基因ID
- 383
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UniProt
- P05089
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途径
- Cellular Response to Molecule of Bacterial Origin
抗原
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