GNAQ 抗体 (N-Term)
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北京 101111
Quick Overview for GNAQ 抗体 (N-Term) (ABIN6719526)
抗原
See all GNAQ 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- N-Term
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原理
- Anti-GNAQ Antibody (monoclonal, 13H4)
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序列
- KYEHNKAHAQ LVREVDVEKV SAFENPYVDA IKSLWND
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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预测反应
- identical to the related mouse,rat sequences.
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产品特性
- Anti-GNAQ Antibody.(monoclonal, 13H4). Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human GNAQ, identical to the related mouse and rat sequences.
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亚型
- IgG2b
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anti-Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ) (Center) antibody
GNAQ 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ) (AA 101-200) antibodyGNAQ 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3B9 unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ) (AA 51-150) antibodyGNAQ 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ) (N-Term) antibodyGNAQ 适用: 人, 小鼠, 大鼠 WB, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ) (AA 162-175) antibodyVerified GNAQ 适用: 人, 小鼠, 大鼠, Pig WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ) antibodyKD Validated GNAQ 适用: 人 WB, FACS, ICC 宿主: 兔 Monoclonal 23GB1295 unconjugated Recombinant Antibody
anti-Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ) (AA 71-120) antibodyGNAQ 适用: 人, 小鼠, 大鼠, 犬, Cow, 斑马鱼, Pig, 豚鼠, 马, 猴, Bat, 小鸡, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ) (AA 1-359) antibodyGNAQ 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ) (AA 1-359) antibodyGNAQ 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ) (AA 1-359) antibodyGNAQ 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Western blot, 0.1-0.5 μg/mL Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL Flow Cytometry (Fixed), 1-3 μg/1x106 cells
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说明
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Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- GNAQ (Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ))
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别名
- GNAQ
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背景
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Background: Guanine nucleotide-binding protein G (q) subunit alpha is a protein that in humans is encoded by the GNAQ gene. Guanine nucleotide-binding proteins are a family of heterotrimeric proteins that couple cell surface, 7-transmembrane domain receptors to intracellular signaling pathways. Receptor activation catalyzes the exchange of GDP for GTP bound to the inactive G protein alpha subunit resulting in a conformational change and dissociation of the complex. The G protein alpha and beta-gamma subunits are capable of regulating various cellular effectors. Activation is terminated by a GTPase intrinsic to the G-alpha subunit. G-alpha-q is the alpha subunit of one of the heterotrimeric GTP-binding proteins that mediates stimulation of phospholipase C-beta. Mutations in this gene have been found associated to cases of Sturge-Weber syndrome and port-wine stains.
Gene Full Name: G protein subunit alpha q
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分子量
- 42 kDa
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基因ID
- 2776
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UniProt
- P50148
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途径
- JAK/STAT Signaling, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction
抗原
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