INPPL1 抗体 (AA 1172-1258)
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Quick Overview for INPPL1 抗体 (AA 1172-1258) (ABIN6719492)
抗原
See all INPPL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1172-1258
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原理
- Anti-INPPL1 Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-INPPL1 Antibody (ABIN6719492). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human INPPL1 recombinant protein (Position: R1172-K1258).
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亚型
- IgG
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anti-Inositol Polyphosphate Phosphatase-Like 1 (INPPL1) (pTyr1135) antibody
INPPL1 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Inositol Polyphosphate Phosphatase-Like 1 (INPPL1) (AA 701-800) antibodyINPPL1 适用: 小鼠, 大鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Inositol Polyphosphate Phosphatase-Like 1 (INPPL1) (AA 100-310) antibodyINPPL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Inositol Polyphosphate Phosphatase-Like 1 (INPPL1) antibodyINPPL1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Inositol Polyphosphate Phosphatase-Like 1 (INPPL1) (AA 1159-1258) antibodyINPPL1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 10G6 unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL
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说明
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Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- INPPL1 (Inositol Polyphosphate Phosphatase-Like 1 (INPPL1))
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别名
- INPPL1
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背景
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Synonyms: Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2, Inositol polyphosphate phosphatase-like protein 1, INPPL-1, Protein 51C, SH2 domain-containing inositol 5'-phosphatase 2, SH2 domain-containing inositol phosphatase 2, SHIP-2, INPPL1, SHIP2
Tissue Specificity: Widely expressed, most prominently in skeletal muscle, heart and brain. Present in platelets. Expressed in transformed myeloid cells and in primary macrophages, but not in peripheral blood monocytes.
Background: SH2-domain containing Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 is an enzyme that in humans is encoded by the INPPL1 gene. The protein encoded by this gene is an SH2-containing 5'-inositol phosphatase that is involved in the regulation of insulin function. The encoded protein also plays a role in the regulation of epidermal growth factor receptor turnover and actin remodelling. Additionally, this gene supports metastatic growth in breast cancer and is a valuable biomarker for breast cancer.
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分子量
- 150 kDa
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基因ID
- 3636
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UniProt
- O15357
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途径
- Platelet-derived growth Factor Receptor Signaling
抗原
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