POR 抗体 (C-Term) (DyLight 550)
Quick Overview for POR 抗体 (C-Term) (DyLight 550) (ABIN7354707)
抗原
See all POR 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 633-668, C-Term
-
原理
- Anti-Human POR DyLight® 550 conjugated Antibody
-
序列
- RNMARDVQNT FYDIVAELGA MEHAQAVDYI KKLMTK
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-Human POR DyLight® 550 conjugated Antibody -Dyl550. Tested in Flow Cytometry applications. This antibody reacts with Human.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human POR , different from the related mouse and rat sequences by five amino acids.
-
亚型
- IgG
-
-
anti-P450 (Cytochrome) Oxidoreductase (POR) (AA 77-518) antibody
POR 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-P450 (Cytochrome) Oxidoreductase (POR) (AA 1-680) antibodyPOR 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-P450 (Cytochrome) Oxidoreductase (POR) (AA 1-250) antibodyPOR 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-P450 (Cytochrome) Oxidoreductase (POR) (N-Term) antibodyKO Validated POR 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-P450 (Cytochrome) Oxidoreductase (POR) antibodyPOR 适用: 人, 大鼠, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-P450 (Cytochrome) Oxidoreductase (POR) (C-Term) antibodyPOR 适用: 人, 大鼠, 小鼠 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-P450 (Cytochrome) Oxidoreductase (POR) (AA 2-671) antibodyPOR 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-P450 (Cytochrome) Oxidoreductase (POR) (AA 1-680) antibodyPOR 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-P450 (Cytochrome) Oxidoreductase (POR) (C-Term) antibodyKO Validated POR 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-P450 (Cytochrome) Oxidoreductase (POR) (AA 633-668), (C-Term) antibodyPOR 适用: 人, 大鼠, 小鼠 WB, IHC, FACS, ICC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Flow Cytometry (Fixed), 1-3 μg/1x106 cells1. Adachi, M., Asakura, Y., Matsuo, M., Yamamoto, T., Hanaki, K., Arlt, W. POR R457H is a global founder mutation causing Antley-Bixler syndrome with autosomal recessive trait. (Letter) Am. J. Med. Genet. 140A: 633-635, 2006. 2. Miller, W. L. Congenital adrenal hyperplasia. (Letter) New Eng. J. Med. 314: 1321-1322, 1986. 3. Shephard, E. A., Phillips, I. R., Santisteban, I., West, L. F., Palmer, C. N., Ashworth, A., Povey, S. Isolation of a human cytochrome P-450 reductase cDNA clone and localization of the corresponding gene to chromosome 7q11.2. Ann. Hum. Genet. 53: 291-301, 1989.
-
说明
-
Other applications have not been tested. Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
-
-
- POR (P450 (Cytochrome) Oxidoreductase (POR))
-
别名
- POR
-
背景
-
Synonyms: NADPH--cytochrome P450 reductase
Background: POR is a membrane-boundenzyme required for electron transfer from NADPH to cytochrome P450 in the endoplasmic reticulum of theeukaryotic cell. The gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons ly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.
-
分子量
- 39 kDa
-
基因ID
- 5447
-
UniProt
- P16435
-
途径
- Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, SARS-CoV-2 Protein Interactome
抗原
-
