PPIB 抗体 (AA 158-216)
Quick Overview for PPIB 抗体 (AA 158-216) (ABIN6719475)
抗原
See all PPIB 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 158-216
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原理
- Anti-Cyclophilin B PPIB Antibody Picoband® (monoclonal, 11C11)
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Cyclophilin B PPIB Antibody Picoband® (monoclonal, 11C11) (ABIN6719475). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human Cyclophilin B recombinant protein (Position: K158-E216).
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亚型
- IgG1
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anti-Cyclophilin B (PPIB) (AA 34-216) antibody
PPIB 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Cyclophilin B (PPIB) (AA 158-216) antibodyPPIB 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Cyclophilin B (PPIB) (AA 161-195) antibodyPPIB 适用: 人, 小鼠, 大鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB55967 unconjugated
anti-Cyclophilin B (PPIB) (AA 47-216) antibodyPPIB 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal D2 unconjugated
anti-Cyclophilin B (PPIB) (AA 34-216) antibodyPPIB 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cyclophilin B (PPIB) antibodyPPIB 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cyclophilin B (PPIB) antibodyPPIB 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF 宿主: 小鼠 Monoclonal 4D7 unconjugated
anti-Cyclophilin B (PPIB) antibodyPPIB 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 小鼠 Monoclonal 1B3 unconjugated
anti-Cyclophilin B (PPIB) (C-Term) antibodyPPIB 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cyclophilin B (PPIB) (C-Term) antibodyPPIB 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 豚鼠, 斑马鱼, 猴, Hamster, Bat, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
Immunocytochemistry/Immunofluorescence, 2 μg/mL
Flow Cytometry (Fixed), 1-3 μg/1x106 cells
1.Barnes, A. M., Cabral, W. A., Weis, M., Makareeva, E., Mertz, E. L., Leikin, S., Eyre, D., Trujillo, C., Marini, J. C. Absence of FKBP10 in recessive type XI osteogenesis imperfecta leads to diminished collagen cross-linking and reduced collagen deposition in extracellular matrix. Hum. Mutat. 33: 1589-1598, 2012. 2.van Dijk, F. S., Cobben, J. M., Pals, G. Osteogenesis imperfecta, normal collagen folding, and lack of cyclophilin B. (Letter) New Eng. J. Med. 362: 1940-1941, 2010. 3.Watashi, K., Ishii, N., Hijikata, M., Inoue, D., Murata, T., Miyanari, Y., Shimotohno, K.Cyclophilin B is a functional regulator of hepatitis C virus RNA polymerase.Molec. Cell 19: 111-122, 2005. -
说明
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Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- PPIB (Cyclophilin B (PPIB))
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别名
- PPIB
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背景
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Synonyms: Peptidyl-prolyl cis-trans isomerase B, PPIase B, CYP-S1, Cyclophilin B, Rotamase B, S-cyclophilin, SCYLP, PPIB, CYPB
Tissue Specificity: Expressed predominantly in placenta.
Background: Peptidyl-prolyl cis-trans isomerase B, also known as CYPB, is an enzyme that in humans is encoded by the PPIB gene. This gene is mapped to 15q22.31. The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta.
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分子量
- 21 kDa
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基因ID
- 5479
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UniProt
- P23284
抗原
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