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PPIB 抗体 (AA 158-216)

This 小鼠 单克隆 anti-PPIB antibody (Clone 11C11) specifically detects PPIB in WB, IHC, ICC, IF 和 FACS. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN6719475
发货至: 中国
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Quick Overview for PPIB 抗体 (AA 158-216) (ABIN6719475)

抗原

See all PPIB 抗体
PPIB (Cyclophilin B (PPIB))

适用

  • 64
  • 44
  • 40
  • 9
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  • 7
  • 7
  • 5
  • 4
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  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 70
  • 16
  • 1
小鼠

克隆类型

  • 57
  • 30
单克隆

标记

  • 54
  • 14
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  • 2
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This PPIB antibody is un-conjugated

应用范围

  • 79
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  • 2
Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

11C11
  • 抗原表位

    • 9
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 158-216

    原理

    Anti-Cyclophilin B PPIB Antibody (monoclonal, 11C11)

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Cyclophilin B PPIB Antibody (monoclonal, 11C11) (ABIN6719475). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived human Cyclophilin B recombinant protein (Position: K158-E216).

    亚型

    IgG1
  • 应用备注

    Western blot, 0.1-0.5 μg/mL
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
    Immunocytochemistry/Immunofluorescence, 2 μg/mL
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells

    说明

    Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    PPIB (Cyclophilin B (PPIB))

    别名

    PPIB

    背景

    Synonyms: Peptidyl-prolyl cis-trans isomerase B, PPIase B, CYP-S1, Cyclophilin B, Rotamase B, S-cyclophilin, SCYLP, PPIB, CYPB

    Tissue Specificity: Expressed predominantly in placenta.

    Background: Peptidyl-prolyl cis-trans isomerase B, also known as CYPB, is an enzyme that in humans is encoded by the PPIB gene. This gene is mapped to 15q22.31. The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta.

    分子量

    21 kDa

    基因ID

    5479

    UniProt

    P23284
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