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COMT 抗体 (AA 20-265)

This anti-COMT antibody is a 兔多克隆 antibody detecting COMT in WB 和 ELISA. Suitable for 大鼠和小鼠.

产品编号 ABIN6719465

发货至: 中国

Quick Overview for COMT 抗体 (AA 20-265) (ABIN6719465)

抗原

See all COMT 抗体

COMT (Catechol-O-Methyltransferase (COMT))

适用

61
48
40
5
3
3
2
2
2
1
1

大鼠, 小鼠

宿主

兔

克隆类型

多克隆

标记

64
5
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1

This COMT antibody is un-conjugated

应用范围

61
42
29
26
23
13
13
9
8
3
3
3
3
1

Western Blotting (WB), ELISA

Discover our top product COMT Primary Antibody

抗原表位
15

8

8

5

4

4

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 20-265

原理

Anti-COMT Antibody Picoband®

交叉反应（详细）

No cross-reactivity with other proteins.

产品特性

Anti-COMT Antibody Picoband® (ABIN6719465). Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

E. coli-derived mouse COMT recombinant protein (Position: R20-S265).

亚型

IgG
anti-Catechol-O-Methyltransferase (COMT) (Internal Region) antibody
Verified COMT 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-Catechol-O-Methyltransferase (COMT) antibody
KO Validated COMT 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Catechol-O-Methyltransferase (COMT) (N-Term) antibody
Verified COMT 适用: 人 WB, ELISA, FACS 宿主: 山羊 Polyclonal unconjugated

anti-Catechol-O-Methyltransferase (COMT) (AA 52-271) antibody
COMT 适用: 人, 大鼠, 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated

anti-Catechol-O-Methyltransferase (COMT) (AA 1-182) antibody
COMT 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1G4-1A1 unconjugated

anti-Catechol-O-Methyltransferase (COMT) (AA 52-271) antibody
COMT 适用: 人 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-Catechol-O-Methyltransferase (COMT) (AA 1-221) antibody
COMT 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Catechol-O-Methyltransferase (COMT) (AA 1-221) antibody
COMT 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

anti-Catechol-O-Methyltransferase (COMT) (C-Term) antibody
COMT 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Catechol-O-Methyltransferase (COMT) (Internal Region) antibody
COMT 适用: 人, 大鼠, 小鼠, 猴, Cow, Pig, Bat IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Baker, K., Baldeweg, T., Sivagnanasundaram, S., Scambler, P., Skuse, D. COMT val108/158met modifies mismatch negativity and cognitive function in 22q11 deletion syndrome. Biol. Psychiat. 58: 23-31, 2005. 2. Lee, S.-G., Joo, Y., Kim, B., Chung, S., Kim, H.-L., Lee, I., Choi, B., Kim, C., Song, K.Association of Ala72Ser polymorphism with COMT enzyme activity and the risk of schizophrenia in Koreans. Hum. Genet. 116: 319-328, 2005.

说明

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
抗原

COMT (Catechol-O-Methyltransferase (COMT))

别名

Comt

背景

Synonyms: Catechol O-methyltransferase, Comt, Comt1
Background: Catechol O-methyltransferase, also called COMT, is one of the major mammalian enzymes involved in the metabolic degradation of catecholamines. This gene is mapped to 22q11.21. Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini.

分子量

25 kDa, 29 kDa

基因ID

12846

UniProt

O88587

途径

Steroid Hormone Biosynthesis, SARS-CoV-2 Protein Interactome

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