CD160 抗体 (AA 27-159)
Quick Overview for CD160 抗体 (AA 27-159) (ABIN6719459)
抗原
See all CD160 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 27-159
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原理
- Anti-CD160 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti- Antibody Picoband® (ABIN6719459). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human CD160 recombinant protein (Position: I27-S159).
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亚型
- IgG
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anti-CD160 (CD160) antibody (PE)
CD160 适用: 人 FACS 宿主: 小鼠 Monoclonal BY55 PE
anti-CD160 (CD160) (AA 81-159) antibodyCD160 适用: 人, 大鼠 WB, FACS, ELISA, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD160 (CD160) antibodyCD160 适用: 人 FACS, IP 宿主: 小鼠 Monoclonal BY55 unconjugated
anti-CD160 (CD160) antibody (APC)CD160 适用: 人 FACS 宿主: 小鼠 Monoclonal BY55 APC
anti-CD160 (CD160) (AA 37-154) antibodyCD160 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD160 (CD160) (Internal Region) antibodyCD160 适用: 人, 小鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD160 (CD160) (AA 1-181) antibodyCD160 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-CD160 (CD160) (AA 1-181) antibodyCD160 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-CD160 (CD160) (AA 33-171) antibodyCD160 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD160 (CD160) (AA 37-154) antibodyCD160 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Anumanthan A, Bensussan A, Boumsell L, Christ AD, Blumberg RS, Voss SD, Patel AT, Robertson MJ, Nadler LM, Freeman GJ (Oct 1998). "Cloning of BY55, a novel Ig superfamily member expressed on NK cells, CTL, and intestinal intraepithelial lymphocytes". J Immunol. 161 (6): 2780-90. 2. Agrawal S, Marquet J, Freeman GJ, Tawab A, Bouteiller PL, Roth P, Bolton W, Ogg G, Boumsell L, Bensussan A (Apr 1999). "Cutting edge: MHC class I triggering by a novel cell surface ligand costimulates proliferation of activated human T cells". J Immunol. 162 (3): 1223-6. -
说明
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Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- CD160
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别名
- CD160
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背景
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Synonyms: CD160 antigen, Natural killer cell receptor BY55, CD160, BY55
Tissue Specificity: Expression is restricted to functional NK and cytotoxic T lymphocytes. Expressed in viral-specific effector memory and terminally differentiated effector memory CD8+ T cells. Expressed in memory and activated CD4+ T cell subsets. Expressed at high levels in intraepithelial lymphocytes. Expressed in both alpha-beta and gamma-delta CD8+ T cell subsets. Expressed in umbilical vein endothelial cells. Expressed in monocytes and at lower levels in B cells. Isoform 3: Expressed exclusively in activated NK cells.
Background: CD160 antigen is a protein that in humans is encoded by the CD160 gene. It is mapped to 1q21.1. CD160 is a 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 Molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16+ cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab+CD8brightCD95+CD56+CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules.
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分子量
- 27 kDa
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基因ID
- 11126
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UniProt
- O95971
抗原
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