ARNTL2 抗体 (AA 461-575)
Quick Overview for ARNTL2 抗体 (AA 461-575) (ABIN6719445)
抗原
See all ARNTL2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 461-575
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原理
- Anti-ARNTL2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-ARNTL2 Antibody Picoband® (ABIN6719445). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human ARNTL2 recombinant protein (Position: E461-T575).
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亚型
- IgG
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anti-Aryl Hydrocarbon Receptor Nuclear Translocator-Like 2 (ARNTL2) antibody
ARNTL2 适用: 人 WB, FACS, ICC, DB 宿主: 小鼠 Monoclonal ARNTH6B5 unconjugated
anti-Aryl Hydrocarbon Receptor Nuclear Translocator-Like 2 (ARNTL2) (AA 35-84) antibodyARNTL2 适用: 人, 犬 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Aryl Hydrocarbon Receptor Nuclear Translocator-Like 2 (ARNTL2) (C-Term) antibodyARNTL2 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Aryl Hydrocarbon Receptor Nuclear Translocator-Like 2 (ARNTL2) (AA 329-378) antibodyARNTL2 适用: 人, 小鼠, 大鼠, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Aryl Hydrocarbon Receptor Nuclear Translocator-Like 2 (ARNTL2) (C-Term) antibodyARNTL2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Aryl Hydrocarbon Receptor Nuclear Translocator-Like 2 (ARNTL2) (N-Term) antibodyARNTL2 适用: 人, 小鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Ikeda, M., Yu, W., Hirai, M., Ebisawa, T., Honma, S., Yoshimura, K., Honma, K.-I., Nomura, M. cDNA cloning of a novel bHLH-PAS transcription factor superfamily gene, BMAL2: its mRNA expression, subcellular distribution, and chromosomal localization. Biochem. Biophys. Res. Commun. 275: 493-502, 2000. 2. Maemura, K., de la Monte, S. M., Chin, M. T., Layne, M. D., Hsieh, C.-M., Yet, S.-F., Perrella, M. A., Lee, M.-E. CLIF, a novel cycle-like factor, regulates the circadian oscillation of plasminogen activator inhibitor-1 gene expression. J. Biol. Chem. 275: 36847-36851, 2000. -
说明
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Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- ARNTL2 (Aryl Hydrocarbon Receptor Nuclear Translocator-Like 2 (ARNTL2))
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别名
- ARNTL2
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背景
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Synonyms: Cytoskeleton-associated protein 5, Colonic and hepatic tumor overexpressed gene protein, Ch-TOG, CKAP5, KIAA0097
Tissue Specificity: Expressed in fetal brain. Highly expressed in brain and placenta. Lower levels in heart, liver, thymus, kidney and lung. Located to endothelial cells and neuronal cells of the suprachiasmatic nucleus (SCN). Also detected in endothelial cells of the heart, lung and kidney. In the brain, specifically expressed in the thalamus, hippocampus and amygdala.
Background: Aryl hydrocarbon receptor nuclear translocator-like 2, also known as Mop9, Bmal2, Clif, or Arntl2, is a gene. This gene encodes a basic helix-loop-helix transcription factor belonging to the PAS (PER, ARNT, SIM) superfamily. The PAS proteins play important roles in adaptation to low atmospheric and cellular oxygen levels, exposure to certain environmental pollutants, and diurnal oscillations in light and temperature. This protein forms a transcriptionally active heterodimer with the circadian CLOCK protein, the structurally related MOP4, and hypoxia-inducible factors, such as HIF1alpha. Consistent with its role as a biologically relevant partner of circadian and hypoxia factors, this protein is coexpressed in regions of the brain such as the thalamus, hypothalamus, and amygdala. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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分子量
- 71 kDa
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基因ID
- 56938
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途径
- Photoperiodism
抗原
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