PPA2 抗体 (AA 33-334)
Quick Overview for PPA2 抗体 (AA 33-334) (ABIN6719431)
抗原
See all PPA2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 33-334
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原理
- Anti-PPA2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-PPA2 Antibody Picoband® (ABIN6719431). Tested in ELISA, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PPA2 recombinant protein (Position: A33-K334).
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亚型
- IgG
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anti-Pyrophosphatase 2 (PPA2) (AA 180-298) antibody
PPA2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pyrophosphatase 2 (PPA2) (AA 1-334) antibodyPPA2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Pyrophosphatase 2 (PPA2) (AA 1-334) antibodyPPA2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Pyrophosphatase 2 (PPA2) (AA 1-90) antibodyPPA2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Pyrophosphatase 2 (PPA2) (AA 33-100) antibodyPPA2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
Immunohistochemistry, 2-5 μg/mL
Immunocytochemistry/Immunofluorescence, 5 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Guimier, A., Gordon, C. T., Godard, F., Ravenscroft, G., Oufadem, M., Vasnier, C., Rambaud, C., Nitschke, P., Bole-Feysot, C., Masson, C., Dauger, S., Longman, C., and 15 others. Biallelic PPA2 mutations cause sudden unexpected cardiac arrest in infancy. Am. J. Hum. Genet. 99: 666-673, 2016. 2. Kennedy, H., Haack, T. B., Hartill, V., Matakovic, L., Baumgartner, E. R., Potter, H., Mackay, R., Alston, C. L., O'Sullivan, S., McFarland, R., Connolly, G., Gannon, C., and 23 others. Sudden cardiac death due to deficiency of the mitochondrial inorganic pyrophosphatase PPA2. Am. J. Hum. Genet. 99: 674-682, 2016. -
说明
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Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- PPA2 (Pyrophosphatase 2 (PPA2))
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别名
- PPA2
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背景
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Synonyms: Inorganic pyrophosphatase 2, mitochondrial, Pyrophosphatase SID6-306, Pyrophosphate phospho-hydrolase 2, PPase 2, PPA2, HSPC124
Tissue Specificity: Detected in brain, gastric carcinoma, lung, ovary, skeletal muscle, umbilical cord blood and a cell line derived from kidney proximal tubule epithelium.
Background: Inorganic pyrophosphatase 2, mitochondrial is is a protein that in humans is encoded by the PPA2 gene. It is mapped to 4q24. The protein encoded by this gene is localized to the mitochondrion, is highly similar to members of the inorganic pyrophosphatase (PPase) family, and contains the signature sequence essential for the catalytic activity of PPase. PPases catalyze the hydrolysis of pyrophosphate to inorganic phosphate, which is important for the phosphate metabolism of cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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分子量
- 38 kDa
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基因ID
- 27068
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UniProt
- Q9H2U2
抗原
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