NPBWR1 抗体 (AA 58-328)
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- 抗原 See all NPBWR1 抗体
- NPBWR1 (Neuropeptides B/W Receptor 1 (NPBWR1))
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抗原表位
- AA 58-328
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NPBWR1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 原理
- Rabbit IgG polyclonal antibody for GPCR GPR7/NPBWR1 detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
- Rabbit IgG polyclonal antibody for GPCR GPR7/NPBWR1 detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human GPCR GPR7/NPBWR1 recombinant protein (Position: V58-A328).
- 亚型
- IgG
- Top Product
- Discover our top product NPBWR1 Primary Antibody
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anti-Neuropeptides B/W Receptor 1 (NPBWR1) (Extracellular Domain) antibody
NPBWR1 适用: 人, 大鼠 IHC (p), IHC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Neuropeptides B/W Receptor 1 (NPBWR1) (Cytoplasmic Domain) antibodyNPBWR1 适用: 人, 猴 IHC (p), IHC 宿主: 兔 Polyclonal unconjugated
anti-Neuropeptides B/W Receptor 1 (NPBWR1) (Cytoplasmic Domain) antibodyNPBWR1 适用: 人 ELISA, IHC (p), IHC 宿主: 兔 Polyclonal unconjugated
anti-Neuropeptides B/W Receptor 1 (NPBWR1) (C-Term) antibodyNPBWR1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Neuropeptides B/W Receptor 1 (NPBWR1) antibodyNPBWR1 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Neuropeptides B/W Receptor 1 (NPBWR1) (2nd Cytoplasmic Domain) antibodyNPBWR1 适用: 人, Gorilla, 猴 IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Neuropeptides B/W Receptor 1 (NPBWR1) (C-Term) antibodyNPBWR1 适用: 人, Gorilla IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Neuropeptides B/W Receptor 1 (NPBWR1) (2nd Extracellular Domain) antibodyNPBWR1 适用: 人, 大鼠, Gorilla IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Application details: Western blot|0.1-0.5 μg/mL Direct ELISA|0.1-0.5 μg/mL
- 说明
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Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- NPBWR1 (Neuropeptides B/W Receptor 1 (NPBWR1))
- 别名
- NPBWR1 (NPBWR1 产品)
- 别名
- NPBWR1 antibody, GPR7 antibody, Gpr7 antibody, Nbpwr1 antibody, neuropeptides B/W receptor 1 antibody, neuropeptides B and W receptor 1 antibody, NPBWR1 antibody, Npbwr1 antibody
- 背景
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Synonyms: Neuropeptides B/W receptor type 1, G-protein coupled receptor 7, NPBWR1, GPR7
Background: Neuropeptides B/W receptor 1, also known as NPBW1 and GPR7, is a human protein encoded by the NPBWR1 gene. In rodent models, NPBWR1 is over-expressed in Schwann cells associated with neuropathic pain, suggesting it inhibits inflammatory pain responses. Mice without NPBW1 exhibited a stronger hostile reaction to intruders, suggesting NPBW1 has a role in stress responses. Early studies indicated that NPB and NPW had a complex effect on appetite, but generally led to anorexia.[12] Similarly, male rats lacking NPBWR1 exhibited hyperphagiaand adult-onset obesity, though why female rats are unaffected is unknown. Researchers speculated that activating these pathways might decrease obesity, and synthesized a small-molecule ligand that is capable of stimulating both receptors at low concentrations.
- 基因ID
- 2831
- UniProt
- P48145
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