AIP 抗体 (AA 91-330)
Quick Overview for AIP 抗体 (AA 91-330) (ABIN6719423)
抗原
See all AIP 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 91-330
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原理
- Anti-ARA9/AIP Antibody Picoband® (monoclonal, 10G8)
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-ARA9/AIP Antibody Picoband® (monoclonal, 10G8) (ABIN6719423). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human ARA9 recombinant protein (Position: D91-H330). Human ARA9 shares 95% amino acid (aa) sequence identity with both mouse and rat ARA9.
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亚型
- IgG2b
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anti-Aryl Hydrocarbon Receptor Interacting Protein (AIP) antibody
AIP 适用: 人 WB, ICC, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-Aryl Hydrocarbon Receptor Interacting Protein (AIP) (AA 156-249) antibodyAIP 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3D3 unconjugated
anti-Aryl Hydrocarbon Receptor Interacting Protein (AIP) antibodyAIP 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aryl Hydrocarbon Receptor Interacting Protein (AIP) (AA 101-150) antibodyAIP 适用: 人, 斑马鱼 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Aryl Hydrocarbon Receptor Interacting Protein (AIP) antibodyAIP 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 1B6 unconjugated
anti-Aryl Hydrocarbon Receptor Interacting Protein (AIP) antibodyAIP 适用: 人, 小鼠, 大鼠 WB, IHC, IP, ICC, IHC (p), IF, ChIP 宿主: 小鼠 Monoclonal 35-2 unconjugated
anti-Aryl Hydrocarbon Receptor Interacting Protein (AIP) (AA 105-294) antibodyAIP 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aryl Hydrocarbon Receptor Interacting Protein (AIP) (Internal Region) antibodyAIP 适用: 人, 小鼠 WB, IHC, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Aryl Hydrocarbon Receptor Interacting Protein (AIP) (N-Term) antibodyAIP 适用: 小鼠, 大鼠, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Aryl Hydrocarbon Receptor Interacting Protein (AIP) (C-Term) antibodyVerified AIP 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
Immunocytochemistry/Immunofluorescence, 2 μg/mL
Flow Cytometry (Fixed), 1-3 μg/1x106 cells
1. Carver LA, Bradfield CA (April 1997). "Ligand-dependent interaction of the aryl hydrocarbon receptor with a novel immunophilin homolog in vivo". J. Biol. Chem. 272(17): 11452-6. 2. Kuzhandaivelu, N., Cong, Y.-S., Inouye, C., Yang, W.-M., Seto, E. XAP2, a novel hepatitis B virus X-associated protein that inhibits X transactivation. Nucleic Acids Res. 24: 4741-4750, 1996. 3. Occhi G, Trivellin G, Ceccato F, et al. (2010). "Prevalence of AIP mutations in a large series of sporadic Italian acromegalic patients and evaluation of CDKN1B status in acromegalic patients with multiple endocrine neoplasia.". Eur. J. Endocrinol. 163 (3): 369-376. -
说明
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Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- AIP (Aryl Hydrocarbon Receptor Interacting Protein (AIP))
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别名
- AIP
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背景
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Synonyms: H receptor-interacting protein, AIP, Aryl-hydrocarbon receptor-interacting protein, HBV X-associated protein 2, XAP-2, Immunophilin homolog ARA9, AIP, XAP2
Tissue Specificity: Widely expressed. Higher levels seen in the heart, placenta and skeletal muscle. Not expressed in the liver.
Background: AIP, also known as, ARA9 or XAP-2, is a protein that in humans is encoded by the AIP gene. This gene is mapped to 11q13.2. The encoded protein is found in the cytoplasm as part of a multiprotein complex, but upon binding of ligand is transported to the nucleus. AIP may play a positive role in aryl hydrocarbon receptor-mediated signalling possibly by influencing its receptivity for ligand and/or its nuclear targeting. It has been shown that AIP is the cellular negative regulator of the hepatitis B virus (HBV) X protein. AIP mutations may be the cause of a familial form of acromegaly, familial isolated pituitary adenoma (FIPA).
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分子量
- 38 kDa
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基因ID
- 9049
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UniProt
- O00170
抗原
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