ITGA6 抗体 (AA 189-917)
Quick Overview for ITGA6 抗体 (AA 189-917) (ABIN6719411)
抗原
See all ITGA6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 189-917
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原理
- Anti-Integrin alpha 6/ITGA6 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Integrin alpha 6/ITGA6 Antibody Picoband® (ABIN6719411). Tested in Flow Cytometry, ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Integrin alpha 6/ITGA6 recombinant protein (Position: Q189-K917).
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亚型
- IgG
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anti-Integrin, alpha 6 (ITGA6) (Internal Region) antibody
ITGA6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha 6 (ITGA6) antibodyITGA6 适用: 人 FACS, IHC, ELISA, IF 宿主: 小鼠 Monoclonal 129CT49-6-5 unconjugated
anti-Integrin, alpha 6 (ITGA6) (Ser1064) antibodyITGA6 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha 6 (ITGA6) (AA 1082-1110), (C-Term) antibodyITGA6 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB18006 unconjugated
anti-Integrin, alpha 6 (ITGA6) (AA 1043-1072), (Isoform 2) antibodyITGA6 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB15309 unconjugated
anti-Integrin, alpha 6 (ITGA6) (AA 625-866) antibodyITGA6 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha 6 (ITGA6) antibody (APC)ITGA6 适用: 人, 小鼠, 犬, Cow, Pig, 绵羊, 马, 兔, Cat, Non-Human Primate FACS 宿主: 大鼠 Monoclonal GoH3 APC
anti-Integrin, alpha 6 (ITGA6) antibodyITGA6 适用: 人, 小鼠, 犬, Pig, 绵羊, Cynomolgus FACS, IP, IHC (fro) 宿主: 大鼠 Monoclonal NKI-GoH3 unconjugated
anti-Integrin, alpha 6 (ITGA6) antibody (PE)ITGA6 适用: 大鼠 FACS 宿主: 小鼠 Monoclonal Mab-5A PE
anti-Integrin, alpha 6 (ITGA6) (Internal Region) antibodyITGA6 适用: 人, 小鼠, 大鼠, 犬, Cow, 猴, 马, Hamster, 豚鼠 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
Flow Cytometry(Fixed), 1-3 μg/1x106 cells
ELISA, 0.1-0.5 μg/mL
1. Notta, F., Doulatov, S., Laurenti, E., Poeppl, A., Jurisica, I., Dick, J. E. Isolation of single human hematopoietic stem cells capable of long-term multilineage engraftment. Science 333: 218-221, 2011. 2. Ruzzi, L., Gagnoux-Palacios, L., Pinola, M., Belli, S., Meneguzzi, G., Zambruno, G., D'Alessio, M. A homozygous mutation in the gene encoding integrin alpha6 in junctional epidermolysis bullosa with pyloric atresia. (Abstract) Medizinische Genetik 9: 13-14, 1997. -
说明
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Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- ITGA6 (Integrin, alpha 6 (ITGA6))
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别名
- ITGA6
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背景
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Synonyms: Integrin alpha-6, CD49 antigen-like family member F, VLA-6, CD49f, Alpha6p, ITGA6
Tissue Specificity: Integrin alpha-6/beta-4 is predominantly expressed by epithelia. Isoforms containing segment X1 are ubiquitously expressed. Isoforms containing segment X1X2 are expressed in heart, kidney, placenta, colon, duodenum, myoblasts and myotubes, and in a limited number of cell lines, they are always coexpressed with the ubiquitous isoform containing segment X1. In some tissues (e.g. Salivary gland), isoforms containing cytoplasmic segment A and isoforms containing segment B are detected while in others, only isoforms containing one cytoplasmic segment are found (segment A in epidermis and segment B in kidney).
Background: Integrin alpha-6, also called VLA-6 or ITGA6B is a protein that in humans is encoded by the ITGA6 gene. This gene is mapped to 2q31.1. The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Integrin alpha-6/beta-1 is a receptor for laminin on platelets. Integrin alpha-6/beta-4 is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome.
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分子量
- 127 kDa
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基因ID
- 3655
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UniProt
- P23229
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途径
- CXCR4-mediated Signaling Events, Brown Fat Cell Differentiation, Integrin Complex
抗原
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