Cadherin 4 抗体 (AA 458-641)
Quick Overview for Cadherin 4 抗体 (AA 458-641) (ABIN6719392)
抗原
See all Cadherin 4 (CDH4) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 458-641
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原理
- Anti-R-Cadherin-4 CDH4-Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-R-Cadherin-4 CDH4-Antibody Picoband® (ABIN6719392). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human R Cadherin/CDH4 recombinant protein (Position: K458-D641).
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亚型
- IgG
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anti-Cadherin 4 (CDH4) (AA 175-203), (N-Term) antibody
CDH4 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB13654 unconjugated
anti-Cadherin 4 (CDH4) (AA 182-211), (N-Term) antibodyCDH4 适用: 人 WB, IF, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 4 (CDH4) (AA 635-734) antibodyCDH4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E2 unconjugated
anti-Cadherin 4 (CDH4) (AA 667-916) antibodyCDH4 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 4 (CDH4) antibodyCDH4 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 4 (CDH4) (AA 635-734) antibodyCDH4 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Cadherin 4 (CDH4) (AA 175-203) antibodyCDH4 适用: 人 WB, IHC, IF, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 4 (CDH4) (Internal Region) antibodyCDH4 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 4 (CDH4) (AA 431-480) antibodyCDH4 适用: 人, 小鼠, 大鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 4 (CDH4) (AA 757-916) antibodyCDH4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
Flow Cytometry (Fixed), 1-3 μg/1x106 cells
ELISA, 0.1-0.5 μg/mL
1. Chalmers, I. J., Hofler, H., Atkinson, M. J. Mapping of a cadherin gene cluster to a region of chromosome 5 subject to frequent allelic loss in carcinoma. Genomics 57: 160-163, 1999. 2. Suzuki, S., Sano, K., Tanihara, H. Diversity of the cadherin family: evidence for eight new cadherins in nervous tissue. Cell Regul. 2: 261-270, 1991. 3. Tanihara, H., Sano, K., Heimark, R. L., St. John, T., Suzuki, S. Cloning of five human cadherins clarifies characteristic features of cadherin extracellular domain and provides further evidence for two structurally different types of cadherin. Cell Adhes. Commun. 2: 15-26, 1994. -
说明
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Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Cadherin 4 (CDH4)
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别名
- CDH4
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背景
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Synonyms: Cadherin-4, Retinal cadherin, R-CAD, R-cadherin, CDH4
Tissue Specificity: Expressed mainly in brain but also found in other tissues.
Background: Cadherin-4 is a protein that in humans is encoded by the CDH4 gene. It is mapped to 20q13.33. This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene.
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分子量
- 125 kDa
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基因ID
- 1002
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UniProt
- P55283
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途径
- Cell-Cell Junction Organization, Regulation of Cell Size
抗原
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