SRI 抗体
Quick Overview for SRI 抗体 (ABIN6719388)
抗原
See all SRI 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Anti-SRI Antibody Picoband®
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序列
- TVDPQELQKA LTTMGFRLSP QAVNSIAKRY
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-SRI Antibody Picoband® (ABIN6719388). Tested in Flow Cytometry, IF, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human SRI, which shares 93.3% amino acid (aa) sequence identity with both mouse and rat SRI.
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亚型
- IgG
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anti-Sorcin (SRI) (AA 1-198) antibody
SRI 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E12 unconjugated
anti-Sorcin (SRI) (AA 1-198) antibodySRI 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Sorcin (SRI) (AA 1-198) antibodySRI 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sorcin (SRI) antibodyKO Validated SRI 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Sorcin (SRI) (AA 29-169) antibodySRI 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sorcin (SRI) (C-Term) antibodySRI 适用: 人, 大鼠, 马, 犬, Cow, 绵羊, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Sorcin (SRI) (AA 96-145) antibodySRI 适用: 人, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
Immunohistochemistry (Frozen Section), 0.5-1 μg/mL
Immunocytochemistry/Immunofluorescence, 2 μg/mL
Flow Cytometry (Fixed), 1-3 μg/1x106 cells
1. "Entrez Gene: SRI sorcin". 2. Meyers, M B, Pickel V M, Sheu S S, Sharma V K, Scotto K W, Fishman G I (Nov 1995). "Association of sorcin with the cardiac ryanodine receptor". J. Biol. Chem. (UNITED STATES) 270 (44): 26411-8. 3. Van der Bliek AM, Baas F, Van der Velde-Koerts T, Biedler JL, Meyers MB, Ozols RF, Hamilton TC, Joenje H, Borst P (Nov 1988). "Genes amplified and overexpressed in human multidrug-resistant cell lines". Cancer Res48 (21): 5927-32. -
说明
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Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- SRI (Sorcin (SRI))
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别名
- SRI
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背景
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Synonyms: Sorcin, 22 kDa protein, CP-22, CP22, V19, SRI
Tissue Specificity: Detected in cardiac myocytes.
Background: Sorcin?is a?protein?that in humans is encoded by the?SRI?gene. It is mapped to 7q21.1. This gene encodes a calcium-binding protein with multiple E-F hand domains that relocates from the cytoplasm to the sarcoplasmic reticulum in response to elevated calcium levels. In addition to regulating intracellular calcium homeostasis it also modulates excitation-contraction coupling in the heart. Alternative splicing results in multiple transcript variants encoding distinct proteins. Multiple pseudogenes exist for this gene.?
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分子量
- 22 kDa
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基因ID
- 6717
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UniProt
- P30626
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途径
- Transition Metal Ion Homeostasis, Maintenance of Protein Location, Negative Regulation of Transporter Activity
抗原
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