KIF15 抗体 (AA 1201-1388)
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北京 101111
Quick Overview for KIF15 抗体 (AA 1201-1388) (ABIN6719385)
抗原
See all KIF15 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1201-1388
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原理
- Anti-KIF15 Antibody
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-KIF15 Antibody. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human KIF15 recombinant protein (Position: M1201-S1388).
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亚型
- IgG
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anti-Kinesin Family Member 15 (KIF15) (AA 1279-1385) antibody
KIF15 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 4D4 unconjugated
anti-Kinesin Family Member 15 (KIF15) (AA 777-804) antibodyKIF15 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB38278 unconjugated
anti-Kinesin Family Member 15 (KIF15) (AA 1-129) antibodyKIF15 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Kinesin Family Member 15 (KIF15) (AA 1079-1128) antibodyKIF15 适用: 人, 犬 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, 0.1-0.5 μg/mL Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL Immunocytochemistry/Immunofluorescence, 5 μg/mL Flow Cytometry (Fixed), 1-3 μg/1x106 cells ELISA, 0.1-0.5 μg/mL
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说明
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Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- KIF15 (Kinesin Family Member 15 (KIF15))
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别名
- KIF15
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背景
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Background: Kinesin family member 15 is a protein that in humans is encoded by the KIF15 gene. It is mapped to 3p21.31. This gene encodes a motor protein that is part of the kinesin superfamily. KIF15 maintains half spindle separation by opposing forces generated by other motor proteins. KIF15 co-localizes with microtubules and actin filaments in both dividing cells and in postmitotic neurons. KIF15 (also known as Kinesin-12 and HKLP2) is a motor protein expressed in all cells during mitosis and in postmitotic neurons undergoing axon growth. KIF15 maintains bipolar microtubule spindle apparatus in dividing cells and shares redundant functions with KIF11. KIF15 is thought to promote spindle assembly by cross-linking and sliding along microtubules creating a separation between centrosomes. HeLa cells depleted of KIF11, with reduced microtubule dynamics, are able to form bipolar spindles from acentrosomal asters in a KIF15 dependent manner. Hence, inhibition of KIF15 function will be a vital therapeutic approach in cancer chemotherapy.
Gene Full Name: kinesin family member 15
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分子量
- 150-160 kDa
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基因ID
- 56992
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UniProt
- Q9NS87
抗原
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