SYT1 抗体 (DyLight 550)
Quick Overview for SYT1 抗体 (DyLight 550) (ABIN7354719)
抗原
See all SYT1 抗体适用
宿主
克隆类型
标记
应用范围
- 
    
- 
                                            
原理
 - Anti-Human Synaptotagmin 1 DyLight® 550 conjugated SYT1 Antibody
 - 
                                            
序列
 - RRPIAQWHTL QVEEEVDAML AVKK
 - 
                                            
交叉反应 (详细)
 - No cross-reactivity with other proteins.
 - 
                                            
产品特性
 - Anti-Human Synaptotagmin 1 DyLight® 550 conjugated SYT1 Antibody -Dyl550. Tested in Flow Cytometry applications. This antibody reacts with Human.
 - 
                                            
纯化方法
 - Immunogen affinity purified.
 - 
                                            
免疫原
 - A synthetic peptide corresponding to a sequence at the C-terminus of human Synaptotagmin 1, identical to the related mouse and rat sequences.
 - 
                                            
亚型
 - IgG
 
 - 
                                            
 - 
    
 - 
    
- 
                                            
应用备注
 - Flow Cytometry (Fixed), 1-3 μg/1x106 cells1. Fernandez-Chacon, R., Konigstorfer, A., Gerber, S. H., Garcia, J., Matos, M. F., Stevens, C. F., Brose, N., Rizo, J., Rosenmund, C., Sudhof, T. C. Synaptotagmin I functions as a calcium regulator of release probability. Nature 410: 41-49, 2001. 2. Poskanzer, K. E., Marek, K. W., Sweeney, S. T., Davis, G. W. Synaptotagmin I is necessary for compensatory synaptic vesicle endocytosis in vivo. Nature 426: 559-563, 2003.
 - 
                                            
说明
 - 
                        
Other applications have not been tested. Optimal dilutions should be determined by end users.
 - 
                                            
限制
 - 仅限研究用
 
 - 
                                            
 - 
    
- 
                                            
状态
 - Liquid
 - 
                                            
浓度
 - Lot specific
 - 
                                            
缓冲液
 - Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
 - 
                                            
储存液
 - Sodium azide
 - 
                                            
注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
 - 
                                            
储存条件
 - -20 °C
 - 
                                            
储存方法
 - At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
 
 - 
                                            
 - 
    
- SYT1 (Synaptotagmin I (SYT1))
 - 
                                            
别名
 - SYT1
 - 
                                            
背景
 - 
                        
Synonyms: Synaptotagmin-1, Synaptotagmin I, SytI, p65, SYT1, SVP65, SYT
Tissue Specificity: Expressed in melanocytes (PubMed:23999003).
Background: Synaptotagmin-1 is a protein that in humans is encoded by the SYT1 gene. The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca (2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin-1 participates in triggering neurotransmitter release at the synapse.
 - 
                                            
分子量
 - 39 kDa
 - 
                                            
基因ID
 - 6857
 - 
                                            
UniProt
 - P21579
 - 
                                            
途径
 - Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
 
抗原
 -