RAB11B 抗体
Quick Overview for RAB11B 抗体 (ABIN6719364)
抗原
See all RAB11B 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Anti-RAB11B Antibody Picoband®
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序列
- QKQIADRAAH DESPGNNVVD ISVPPTTDGQ KPNKLQCC
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-RAB11B Antibody Picoband® (ABIN6719364). Tested in Flow Cytometry, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human RAB11B, which shares 97.4% and 100% amino acid (aa) sequence identity with mouse and rat RAB11B, respectively.
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亚型
- IgG
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anti-RAB11B, Member RAS Oncogene Family (RAB11B) (C-Term) antibody
RAB11B 适用: 人, 小鼠, 大鼠, 犬, 山羊, 豚鼠, Cow, Hamster, Pig, 猴, Cat, 小鸡, 驴, 马, 兔, 绵羊, Avian WB, IF 宿主: 山羊 Polyclonal unconjugated
anti-RAB11B, Member RAS Oncogene Family (RAB11B) (C-Term) antibodyRAB11B 适用: 人, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-RAB11B, Member RAS Oncogene Family (RAB11B) (AA 130-215) antibodyRAB11B 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-RAB11B, Member RAS Oncogene Family (RAB11B) (AA 2-215) antibodyRAB11B 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-RAB11B, Member RAS Oncogene Family (RAB11B) (AA 1-218) antibodyRAB11B 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-RAB11B, Member RAS Oncogene Family (RAB11B) (AA 164-193), (C-Term) antibodyRAB11B 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB30239 unconjugated
anti-RAB11B, Member RAS Oncogene Family (RAB11B) (C-Term) antibodyRAB11B 适用: 人, 小鼠, 大鼠, 犬, 山羊, 豚鼠, Cow, 斑马鱼, Hamster, Pig, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
Immunohistochemistry (Frozen Section), 0.5-1 μg/mL
Immunocytochemistry, 0.5-1 μg/mL
Flow Cytometry (Fixed), 1-3 μg/1x106 cells
1. Gross, M. B. Personal Communication. Baltimore, Md. 7/25/2014. 2. Lamers, I. J. C., Reijnders, M. R. F., Venselaar, H., Kraus, A., DDD Study, Jansen, S., de Vries, B. B. A., Houge, G., Gradek, G. A., Seo, J., Choi, M., Chae, J.-H., and 11 others. Recurrent de novo mutations disturbing the GTP/GDP binding pocket of RAB11B cause intellectual disability and a distinctive brain phenotype. Am. J. Hum. Genet. 101: 824-832, 2017. 3. Zhu, A. X., Zhao, Y., Flier, J. S. Molecular cloning of two small GTP-binding proteins from human skeletal muscle. Biochem. Biophys. Res. Commun. 205: 1875-1882, 1994. -
说明
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Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- RAB11B (RAB11B, Member RAS Oncogene Family (RAB11B))
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别名
- RAB11B
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背景
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Synonyms: Ras-related protein Rab-11B, GTP-binding protein YPT3, RAB11B, YPT3
Tissue Specificity: Expressed in all tissues except liver. Highest levels found in heart, skeletal muscle and pancreas.
Background: Ras-related protein Rab-11B is a protein that in humans is encoded by the RAB11B gene. It is mapped to 19p13.2. The Ras superfamily of small GTP-binding proteins, which includes the Ras, Ral, Rho, Rap, and Rab families, is involved in controlling a diverse set of essential cellular functions. The Rab family, including RAB11B, appears to play a critical role in regulating exocytotic and endocytotic pathways.
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分子量
- 24 kDa
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基因ID
- 9230
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UniProt
- Q15907
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途径
- Hormone Transport, Carbohydrate Homeostasis
抗原
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