PON1 抗体 (AA 30-274)
Quick Overview for PON1 抗体 (AA 30-274) (ABIN7354529)
抗原
See all PON1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 30-274
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原理
- Rabbit IgG polyclonal antibody for PON1 detection. Tested with ELISA(Det) in Mouse.
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交叉反应 (详细)
- No cross reactivity with other proteins.
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产品特性
- Rabbit IgG polyclonal antibody for PON1 detection. Tested with ELISA(Det) in Mouse.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived mouse PON1 recombinant protein (Position: A30-D274).
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亚型
- IgG
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应用备注
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Application details: ELISA(Det)|0.1-0.5 μg/mL
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说明
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Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- PON1 (Paraoxonase 1 (PON1))
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别名
- Pon1
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背景
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Synonyms: Serum paraoxonase/arylesterase 1, PON 1
Background: Serum paraoxonase/arylesterase 1 (PON1), also known as aromatic esterase 1, is an enzyme that in humans is encoded by the PON1 gene. It is mapped to 7q21.3. This gene has esterase and more specifically paraoxonase activity. PON1 is responsible for hydrolysing organophosphate pesticides and nerve gasses. Polymorphisms in the PON1 gene significantly affect the catalytic ability of the enzyme. PON1 (paraoxonase 1) is also a major anti-atherosclerotic component of high-density lipoprotein (HDL). The PON1 gene is activated by PPAR-γ, which increases synthesis and release of paraoxonase 1 enzyme from the liver, reducing atherosclerosis.
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基因ID
- 18979
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UniProt
- P52430
抗原
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