MOG 抗体
Quick Overview for MOG 抗体 (ABIN6719344)
抗原
See all MOG 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Anti-Myelin oligodendrocyte glycoprotein/MOG Antibody Picoband®
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序列
- RVVHLYRNGK DQDGDQAPEY RGRTELLKDA IGEGK
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Myelin oligodendrocyte glycoprotein/MOG Antibody Picoband® (ABIN6719344). Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human Myelin oligodendrocyte glycoprotein/MOG, which shares 85.7% and 88.6% amino acid (aa) sequence identity with mouse and rat Myelin oligodendrocyte glycoprotein/MOG, respectively.
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亚型
- IgG
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anti-Myelin Oligodendrocyte Glycoprotein (MOG) (AA 30-149) antibody
MOG 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myelin Oligodendrocyte Glycoprotein (MOG) (AA 29-153) antibodyMOG 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myelin Oligodendrocyte Glycoprotein (MOG) (AA 28-152) antibodyMOG 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myelin Oligodendrocyte Glycoprotein (MOG) (C-Term) antibodyMOG 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Myelin Oligodendrocyte Glycoprotein (MOG) antibodyMOG 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Myelin Oligodendrocyte Glycoprotein (MOG) (AA 35-55) antibodyMOG 适用: 小鼠, 大鼠 WB, ICC, ELISA, FACS, IF (p), IHC (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Myelin Oligodendrocyte Glycoprotein (MOG) (AA 30-149) antibodyMOG 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Myelin Oligodendrocyte Glycoprotein (MOG) (AA 30-154) antibodyMOG 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Myelin Oligodendrocyte Glycoprotein (MOG) antibodyMOG 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Myelin Oligodendrocyte Glycoprotein (MOG) (AA 1-295) antibodyMOG 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Pham-Dinh D, Della Gaspera B, Kerlero de Rosbo N, Dautigny A (September 1995). "Structure of the human myelin/oligodendrocyte glycoprotein gene and multiple alternative spliced isoforms". Genomics. 2. Pham-Dinh D, Jones EP, Pitiot G, Della Gaspera B, Daubas P, Mallet J, Le Paslier D, Fischer Lindahl K, Dautigny A (1995). 3. "Physical mapping of the human and mouse MOG gene at the distal end of the MHC class Ib region". 4. Immunogenetics. Roth MP, Malfroy L, Offer C, Sevin J, Enault G, Borot N, Pontarotti P, Coppin H (July 1995). 5. "The human myelin oligodendrocyte glycoprotein (MOG) gene: complete nucleotide sequence and structural characterization". Genomics. 6. Berger, T., Innsbruck Medical University Dept. of Neurology interviewed by S. Gillooly, Nov. 24, 2008. -
说明
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Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- MOG (Myelin Oligodendrocyte Glycoprotein (MOG))
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别名
- MOG
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背景
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Synonyms: Myelin-oligodendrocyte glycoprotein, MOG
Tissue Specificity: Found exclusively in the CNS, where it is localized on the surface of myelin and oligodendrocyte cytoplasmic membranes.
Background: Myelin oligodendrocyte glycoprotein (MOG) is a glycoprotein believed to be important in the myelination of nerves in the central nervous system (CNS). In humans this protein is encoded by the MOG gene. This gene is mapped to 6p22.1. It is speculated to serve as a necessary "adhesion molecule" to provide structural integrity to the myelin sheath and is known to develop late on the oligodendrocyte. The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified.
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分子量
- 26 kDa
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基因ID
- 4340
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UniProt
- Q16653
抗原
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