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IL-22 抗体 (AA 34-179)

This anti-IL-22 antibody is a 小鼠 单克隆 antibody detecting IL-22 in WB 和 FACS. Suitable for 人.
产品编号 ABIN6719333
发货至: 中国

Quick Overview for IL-22 抗体 (AA 34-179) (ABIN6719333)

抗原

See all IL-22 (IL22) 抗体
IL-22 (IL22) (Interleukin 22 (IL22))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This IL-22 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS)

克隆位点

7F2
  • 抗原表位

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    AA 34-179

    原理

    Anti-IL22 Antibody Picoband® (monoclonal, 7F2)

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-IL22 Antibody Picoband® (monoclonal, 7F2) (ABIN6719333). Tested in Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived human IL-22 recombinant protein (Position: A34-I179). Human IL-22 shares 81.4% amino acid (aa) sequence identity with mouse IL-22.

    亚型

    IgG1
  • 应用备注

    Western blot, 0.1-0.5 μg/mL
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells
    1. Dumoutier, L., Van Roost, E., Ameye, G., Michaux, L., Renauld, J.-C. IL-TIF/IL-22: genomic organization and mapping of the human and mouse genes. Genes Immunity 1: 488-494, 2000. 2. Moore KW, de Waal Malefyt R, Coffman RL, O'Garra A (2001). "Interleukin-10 and the interleukin-10 receptor". Annu. Rev. Immunol. 19: 683-765.

    说明

    Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Lyophilized

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    IL-22 (IL22) (Interleukin 22 (IL22))

    别名

    IL22

    背景

    Synonyms: Interleukin-22, IL-22, Cytokine Zcyto18, IL-10-related T-cell-derived-inducible factor, IL-TIF, IL22, ILTIF, ZCYTO18, UNQ3099/PRO10096

    Background: Interleukin-22 (IL-22), also known as ILTIF, is protein that in humans is encoded by the IL22 gene. IL-22 a member of a group of cytokines called the IL-10 family or IL-10 superfamily, a class of potent mediators of cellular inflammatory responses. Using FISH, the IL22 gene is mapped to chromosome 12q15, close to the IFNG and the herpesvirus saimiri-induced AK155 genes. IL-22 can contribute to immune disease through the stimulation of inflammatory responses, S100s and defensins. It also promotes hepatocyte survival in the liver and epithelial cells in the lung and gut similar to IL-10. In some contexts, the pro-inflammatory versus tissue-protective functions of IL-22 are regulated by the often co-expressed cytokine IL-17A.

    分子量

    24 kDa

    基因ID

    50616
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