IL-22 抗体 (AA 34-179) (DyLight 488)
Quick Overview for IL-22 抗体 (AA 34-179) (DyLight 488) (ABIN6719331)
抗原
See all IL-22 (IL22) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 34-179
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原理
- Anti-Human IL22 DyLight® 488 conjugated Antibody(monoclonal, 7F2)
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Human IL22 DyLight® 488 conjugated Antibody (monoclonal, 7F2) (ABIN6719333)-Dyl488. Tested in Flow Cytometry applications. This antibody reacts with Human.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human IL-22 recombinant protein (Position: A34-I179). Human IL-22 shares 81.4% amino acid (aa) sequence identity with mouse IL-22.
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亚型
- IgG1
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anti-Interleukin 22 (IL22) (AA 35-179) antibody
IL22 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 22 (IL22) (AA 34-179) antibodyIL22 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 22 (IL22) (AA 34-179) antibodyIL22 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 22 (IL22) antibodyIL22 适用: 人 WB, ELISA, IHC, Neut, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 22 (IL22) (AA 34-179) antibodyIL22 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 22 (IL22) antibodyIL22 适用: 人, 小鼠, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 22 (IL22) (AA 34-179) antibodyIL22 适用: 人 FACS 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 22 (IL22) (AA 34-179) antibodyIL22 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 22 (IL22) (C-Term) antibodyIL22 适用: 人, 小鼠, 大鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 22 (IL22) (AA 1-179) antibodyIL22 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow Cytometry (Fixed), 1-3 μg/1x106 cells1. Dumoutier, L., Van Roost, E., Ameye, G., Michaux, L., Renauld, J.-C. IL-TIF/IL-22: genomic organization and mapping of the human and mouse genes. Genes Immunity 1: 488-494, 2000. 2. Moore KW, de Waal Malefyt R, Coffman RL, O'Garra A (2001). "Interleukin-10 and the interleukin-10 receptor". Annu. Rev. Immunol. 19: 683-765.
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说明
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Other applications have not been tested. Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- Lot specific
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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- IL-22 (IL22) (Interleukin 22 (IL22))
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别名
- IL22
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背景
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Synonyms: Interleukin-22, IL-22, Cytokine Zcyto18, IL-10-related T-cell-derived-inducible factor, IL-TIF, IL22, ILTIF, ZCYTO18, UNQ3099/PRO10096
Tissue Specificity: Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in various body fluids, such as the cerebrospinal fluid and plasma. Expressed in highest levels in the epididymis, vas deferens, brain, thymus, and ovary and the lowest in the submandibular gland.
Background: Interleukin-22 (IL-22), also known as ILTIF, is protein that in humans is encoded by the IL22 gene. IL-22 a member of a group of cytokines called the IL-10 family or IL-10 superfamily, a class of potent mediators of cellular inflammatory responses. Using FISH, the IL22 gene is mapped to chromosome 12q15, close to the IFNG and the herpesvirus saimiri-induced AK155 genes. IL-22 can contribute to immune disease through the stimulation of inflammatory responses, S100s and defensins. It also promotes hepatocyte survival in the liver and epithelial cells in the lung and gut similar to IL-10. In some contexts, the pro-inflammatory versus tissue-protective functions of IL-22 are regulated by the often co-expressed cytokine IL-17A.
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分子量
- 39 kDa
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基因ID
- 50616
抗原
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