IGLL1 抗体
Quick Overview for IGLL1 抗体 (ABIN6719329)
抗原
See all IGLL1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- Anti-IGLL1 Antibody Picoband®
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-IGLL1 Antibody Picoband® (ABIN6719329). Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E. coli-derived human IGLL1 recombinant protein (L38-S213).
-
亚型
- IgG
-
-
anti-Immunoglobulin lambda-Like Polypeptide 1 (IGLL1) (AA 1-213) antibody
IGLL1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Immunoglobulin lambda-Like Polypeptide 1 (IGLL1) (AA 29-201) antibodyIGLL1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Immunoglobulin lambda-Like Polypeptide 1 (IGLL1) (AA 1-213) antibodyIGLL1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Immunoglobulin lambda-Like Polypeptide 1 (IGLL1) (C-Term) antibodyIGLL1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Immunoglobulin lambda-Like Polypeptide 1 (IGLL1) antibodyIGLL1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Immunoglobulin lambda-Like Polypeptide 1 (IGLL1) (N-Term) antibodyIGLL1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Immunoglobulin lambda-Like Polypeptide 1 (IGLL1) (AA 64-113) antibodyIGLL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Immunoglobulin lambda-Like Polypeptide 1 (IGLL1) (AA 112-206) antibodyIGLL1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Kudo, A., Melchers, F. A second gene, Vpre-B in the lambda 5 locus of the mouse, which appears to be selectively expressed in pre-B lymphocytes. EMBO J. 6: 2267-2272, 1987. 2. Linnebank, M., Tschiedel, E., Haberle, J., Linnebank, A., Willenbring, H., Kleijer, W. J., Koch, H. G. Argininosuccinate lyase (ASL) deficiency: mutation analysis in 27 patients and a completed structure of the human ASL gene. Hum. Genet. 111: 350-359, 2002. 3. Mattei, M.-G., Fumoux, F., Roeckel, N., Fougereau, M., Schiff, C. The human pre-B-specific lambda-like cluster is located in the 22q11.2-22q12.3 region, distal to the IgC-lambda locus. Genomics 9: 544-546, 1991. -
说明
-
Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
- IGLL1 (Immunoglobulin lambda-Like Polypeptide 1 (IGLL1))
-
别名
- IGLL1
-
背景
-
Synonyms: Immunoglobulin lambda-like polypeptide 1, CD179 antigen-like family member B, Ig lambda-5, Immunoglobulin omega polypeptide, Immunoglobulin-related protein 14.1, CD179b, IGLL1, IGL1
Tissue Specificity: Expressed only in pre-B-cells and a special B-cell line (which is surface Ig negative).
Background: Immunoglobulin lambda-like polypeptide 1 is a protein that in humans is encoded by the IGLL1 gene. It is mapped to 22q11.23. The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene.
-
分子量
- 26 kDa
-
基因ID
- 3543
-
UniProt
- P15814
-
途径
- Regulation of Cell Size
抗原
-
