HAVCR1 抗体 (AA 58-289)
Quick Overview for HAVCR1 抗体 (AA 58-289) (ABIN6719323)
抗原
See all HAVCR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 58-289
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原理
- Anti-TIM 1/HAVCR1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-TIM 1/HAVCR1 Antibody Picoband® (ABIN6719323). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human TIM 1 recombinant protein (Position: Q58-K289).
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亚型
- IgG
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anti-Hepatitis A Virus Cellular Receptor 1 (HAVCR1) (AA 332-348), (C-Term) antibody
HAVCR1 适用: 人 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Hepatitis A Virus Cellular Receptor 1 (HAVCR1) (AA 21-240) antibodyHAVCR1 适用: 人 WB 宿主: 小鼠 Monoclonal C2 unconjugated
anti-Hepatitis A Virus Cellular Receptor 1 (HAVCR1) (AA 22-235) antibodyHAVCR1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hepatitis A Virus Cellular Receptor 1 (HAVCR1) (AA 1-364) antibodyHAVCR1 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 2G11 unconjugated
anti-Hepatitis A Virus Cellular Receptor 1 (HAVCR1) (AA 70-290) antibodyHAVCR1 适用: 人, 小鼠 WB, ELISA 宿主: 小鼠 Monoclonal 3D9F5 unconjugated
anti-Hepatitis A Virus Cellular Receptor 1 (HAVCR1) (AA 70-290) antibodyHAVCR1 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3A12E10 unconjugated
anti-Hepatitis A Virus Cellular Receptor 1 (HAVCR1) (AA 21-240) antibodyHAVCR1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hepatitis A Virus Cellular Receptor 1 (HAVCR1) (AA 21-293) antibodyHAVCR1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hepatitis A Virus Cellular Receptor 1 (HAVCR1) (AA 22-235) antibodyHAVCR1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C8 unconjugated
anti-Hepatitis A Virus Cellular Receptor 1 (HAVCR1) (AA 21-290) antibodyHAVCR1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
ELISA (Cap), 1-5 μg/mL
1. de Souza, A. J., Oriss, T. B., O'Malley, K. J., Ray, A., Kane, L. P. T cell Ig and mucin 1 (TIM-1) is expressed on in vivo-activated T cells and provides a costimulatory signal for T cell activation. Proc. Nat. Acad. Sci. 102: 17113-17118, 2005. 2. Feigelstock, D., Thompson, P., Mattoo, P., Zhang, Y., Kaplan, G. G. The human homolog of HAVcr-1 codes for a hepatitis A virus cellular receptor. J. Virol. 72: 6621-6628, 1998. -
说明
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Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- HAVCR1 (Hepatitis A Virus Cellular Receptor 1 (HAVCR1))
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别名
- HAVCR1
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背景
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Synonyms: Hepatitis A virus cellular receptor 1, HAVcr-1, Kidney injury molecule 1, KIM-1, T-cell immunoglobulin and mucin domain-containing protein 1, TIMD-1, T-cell immunoglobulin mucin receptor 1, TIM, TIM-1, T-cell membrane protein 1, HAVCR1, KIM1, TIM1, TIMD1
Tissue Specificity: Widely expressed, with highest levels in kidney and testis. Expressed by activated CD4+ T-cells during the development of helper T-cells responses.
Background: KIM1 (KIDNEY INJURY MOLECULE 1), also known as HAVCR1, HAVCR or TIM1, is a protein that in humans is encoded by the KIM1 gene. The KIM1 gene is mapped to 5q33.3. Biochemical, mutational, and cell adhesion analyses confirm that Tim1 is capable of homophilic Tim-Tim interactions. The features identified in murine KIM1 are conserved in human KIM1. The KIM1 protein is indeed a receptor for the virus through the infection of canine osteogenic sarcoma cells expressing HAVCR1 with HAV. Using a monoclonal antibody to mouse Tim1, Tim1 is expressed after activation of naive T cells and on T cells differentiated in Th2-polarizing conditions. Ectopic expression of KIM1 during mouse T-cell differentiation leads to production of the Th2-type cytokine Il4, but not the Th1-type cytokine Ifng. KIM1-expressing epithelial cells internalized apoptotic bodies, and Kim1 is ly responsible for phagocytosis in cultured primary rat tubule epithelial cells and in porcine and canine epithelial cell lines.
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分子量
- 39 kDa
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基因ID
- 26762
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UniProt
- Q96D42
抗原
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