Dynamin 1 抗体 (AA 616-667) (DyLight 550)
Quick Overview for Dynamin 1 抗体 (AA 616-667) (DyLight 550) (ABIN7354731)
抗原
See all Dynamin 1 (DNM1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 616-667
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原理
- Anti-Human Dynamin 1 DyLight® 550 conjugated DNM1 Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Human Dynamin 1 DyLight® 550 conjugated DNM1 Antibody -Dyl550. Tested in Flow Cytometry applications. This antibody reacts with Human.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human Dynamin 1 recombinant protein (Position: W616-D667).
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亚型
- IgG
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anti-Dynamin 1 (DNM1) antibody
DNM1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-Dynamin 1 (DNM1) (AA 616-667) antibodyDNM1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Dynamin 1 (DNM1) (AA 572-745) antibodyDNM1 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dynamin 1 (DNM1) (AA 2-245) antibodyDNM1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dynamin 1 (DNM1) antibodyDNM1 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 3G4B6 unconjugated
anti-Dynamin 1 (DNM1) antibodyDNM1 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Dynamin 1 (DNM1) (Ser307) antibodyDNM1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dynamin 1 (DNM1) (C-Term) antibodyDNM1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dynamin 1 (DNM1) (pSer778) antibodyDNM1 适用: 大鼠 WB 宿主: 绵羊 Polyclonal unconjugated
anti-Dynamin 1 (DNM1) (N-Term) antibodyDNM1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow Cytometry (Fixed), 1-3 μg/1x106 cells1. Dhindsa, R. S., Bradrick, S. S., Yao, X., Heinzen, E. L., Petrovski, S., Krueger, B. J., Johnson, M. R., Frankel, W. N., Petrou, S., Boumil, R. M., Goldstein, D. B. Epileptic encephalopathy-causing mutations in DNM1 impair synaptic vesicle endocytosis. Neurol. Genet. 1: e4, 2015. 2. EuroEPINOMICS-RES Consortium, Epilepsy Phenome/Genome Project, Epi4K Consortium. De novo mutations in synaptic transmission genes including DNM1 cause epileptic encephalopathies. Am. J. Hum. Genet. 95: 360-370, 2014.
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说明
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Other applications have not been tested. Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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- Dynamin 1 (DNM1)
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别名
- DNM1
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背景
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Synonyms: Dynamin-1, DNM1, DNM
Background: Dynamin-1 is a protein that in humans is encoded by the DNM1 gene. This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described.
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分子量
- 39 kDa
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基因ID
- 1759
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UniProt
- Q05193
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途径
- Toll-Like Receptors Cascades, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
抗原
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