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CSTB 抗体 (AA 1-98) (DyLight 550)

This anti-CSTB antibody is a 小鼠单克隆 antibody detecting CSTB in FACS. Suitable for 人.

产品编号 ABIN6719308

发货至: 中国

Quick Overview for CSTB 抗体 (AA 1-98) (DyLight 550) (ABIN6719308)

抗原

See all CSTB 抗体

CSTB (Cystatin B (Stefin B) (CSTB))

适用

92
30
24
13
3
3
3
2
2
2
1

人

宿主

小鼠

克隆类型

单克隆

标记

66
19
9
4
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1

This CSTB antibody is conjugated to DyLight 550

应用范围

87
60
36
34
23
18
13
13
11
9
5
4
3
2
1
1
1

Flow Cytometry (FACS)

克隆位点

2B6

Discover our top product CSTB Primary Antibody

抗原表位
26

15

13

5

4

3

3

3

2

2

2

1

1

1

1

1

1
AA 1-98

原理

Anti-Human Stefin B DyLight® 550 conjugated CSTB Antibody(monoclonal, 2B6)

交叉反应（详细）

No cross-reactivity with other proteins.

产品特性

Anti-Human Stefin B DyLight® 550 conjugated CSTB Antibody (monoclonal, 2B6) (ABIN5692840)-Dyl550. Tested in Flow Cytometry applications. This antibody reacts with Human.

纯化方法

Immunogen affinity purified.

免疫原

E. coli-derived human Stefin B recombinant protein (Position: M1-F98). Human Stefin B shares 78.6 % amino acid (aa) sequence identity with both mouse and rat Stefin B.

亚型

IgG1
anti-Cystatin B (Stefin B) (CSTB) (AA 1-98) antibody
CSTB 适用: 人 WB, IHC, ELISA, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Cystatin B (Stefin B) (CSTB) (AA 1-98) antibody
CSTB 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal M2-F1 unconjugated

anti-Cystatin B (Stefin B) (CSTB) (C-Term) antibody
CSTB 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cystatin B (Stefin B) (CSTB) (C-Term) antibody
Verified CSTB 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-Cystatin B (Stefin B) (CSTB) (AA 1-98) antibody
CSTB 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal M1-C1 unconjugated

anti-Cystatin B (Stefin B) (CSTB) (AA 2-98) antibody
CSTB 适用: 大鼠 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal C13 unconjugated

anti-Cystatin B (Stefin B) (CSTB) antibody
CSTB 适用: 人, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Cystatin B (Stefin B) (CSTB) (AA 1-98) antibody
CSTB 适用: 人 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Cystatin B (Stefin B) (CSTB) (AA 51-98) antibody
CSTB 适用: 人 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Cystatin B (Stefin B) (CSTB) (AA 2-98) antibody
CSTB 适用: 大鼠 WB 宿主: 小鼠 Monoclonal C6 unconjugated

应用备注

Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells1. Alakurtti, K., Weber, E., Rinne, R., Theil, G., de Haan, G.-J., Lindhout, D., Salmikangas, P., Saukko, P., Lahtinen, U., Lehesjoki, A.-E. Loss of lysosomal association of cystatin B proteins representing progressive myoclonus epilepsy, EPM1, mutations. Europ. J. Hum. Genet. 13: 208-215, 2005. Note: Erratum: Europ. J. Hum. Genet. 13: 264 only, 2005. 2. Antonarakis, S. Personal Communication. Geneva, Switzerland 4/8/1997. 3. Bespalova, I. N., Adkins, S., Pranzatelli, M., Burmeister, M. Novel cystatin B mutation and diagnostic PCR assay in an Unverricht-Lundborg progressive myoclonus epilepsy patient. Am. J. Med. Genet. 74: 467-471, 1997.

说明

Other applications have not been tested. Optimal dilutions should be determined by end users.

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
抗原

CSTB (Cystatin B (Stefin B) (CSTB))

别名

CSTB

背景

Synonyms: Cystatin-B, CPI-B, Liver thiol proteinase inhibitor, Stefin-B, CSTB, CST6, STFB
Background: Cystatin B (CSTB), also called STFB, is a small protein that is a member of the superfamily of cysteine protease inhibitors. It has been isolated from human spleen and liver and its amino acid sequence has been fully determined. The cystatin B gene is located on 21q22.3. It is widely distributed and is localized mostly intracellularly, but has been found extracellularly. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. Its role is thought to be as a protector against the proteinases leaking from lysosomes. A cystatin B multiprotein complex might have a specific cerebellar function, and that the loss of this function might contribute to the etiopathogenesis of EPM1. Upon differentiation to myotubes, CSTB becomes excluded from the nucleus and lysosomes, suggesting that the subcellular distribution of CSTB is dependent on the differentiation status of the cell.

分子量

39 kDa

基因ID

1476

UniProt

P04080

途径

Response to Water Deprivation

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