COMP 抗体 (AA 505-757)
Quick Overview for COMP 抗体 (AA 505-757) (ABIN6719297)
抗原
See all COMP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 505-757
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原理
- Anti-COMP Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-COMP Antibody Picoband® (ABIN6719297). Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human COMP recombinant protein (Position: Q505-A757).
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亚型
- IgG
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anti-Cartilage Oligomeric Matrix Protein (COMP) (AA 554-753) antibody
COMP 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cartilage Oligomeric Matrix Protein (COMP) (AA 20-160) antibodyCOMP 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Cartilage Oligomeric Matrix Protein (COMP) (AA 314-343) antibodyCOMP 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB21199 unconjugated
anti-Cartilage Oligomeric Matrix Protein (COMP) (AA 123-240) antibodyCOMP 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cartilage Oligomeric Matrix Protein (COMP) (AA 554-753) antibodyCOMP 适用: 小鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Cartilage Oligomeric Matrix Protein (COMP) antibodyCOMP 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cartilage Oligomeric Matrix Protein (COMP) antibodyCOMP 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Cartilage Oligomeric Matrix Protein (COMP) (AA 1-724) antibodyCOMP 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Cartilage Oligomeric Matrix Protein (COMP) (AA 221-320) antibodyCOMP 适用: 人 WB, ELISA, ICC, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cartilage Oligomeric Matrix Protein (COMP) (AA 20-160) antibodyCOMP 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Ballo, R., Briggs, M. D., Cohn, D. H., Knowlton, R. G., Beighton, P. H., Ramesar, R. S. Multiple epiphyseal dysplasia, Ribbing type: a novel point mutation in the COMP gene in a South African family. Am. J. Med. Genet. 68: 396-400, 1997. Note: Erratum: Am. J. Med. Genet. 71: 494 only, 1997. 2. Deere, M., Sanford, T., Ferguson, H. L., Daniels, K., Hecht, J. T. Identification of twelve mutations in cartilage oligomeric matrix protein (COMP) in patients with pseudoachondroplasia. Am. J. Med. Genet. 80: 510-513, 1998. -
说明
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Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- COMP (Cartilage Oligomeric Matrix Protein (COMP))
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别名
- COMP
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背景
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Synonyms: Cartilage oligomeric matrix protein, COMP, Thrombospondin-5, TSP5, COMP
Tissue Specificity: Abundantly expressed in the chondrocyte extracellular matrix, and is also found in bone, tendon, ligament and synovium and blood vessels. Increased amounts are produced during late stages of osteoarthritis in the area adjacent to the main defect.
Background: COMP is a pentameric extracellular matrix protein that catalyzes the assembly of collagens and promotes formation of well-defined fibrils. This gene is mapped to 19q13.32. The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family.
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分子量
- 83 kDa
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基因ID
- 1311
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UniProt
- P49747
抗原
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