Caveolin 3 抗体 (AA 1-55)
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北京 101111
Quick Overview for Caveolin 3 抗体 (AA 1-55) (ABIN6719285)
抗原
See all Caveolin 3 (CAV3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-55
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原理
- Anti-Caveolin-3/CAV3 Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Caveolin-3/CAV3 Antibody (ABIN6719285). Tested in ELISA, IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Caveolin-3/CAV3 recombinant protein (Position: M1-D55).
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亚型
- IgG
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anti-Caveolin 3 (CAV3) antibody
KD Validated CAV3 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 23GB3040 unconjugated Recombinant Antibody
anti-Caveolin 3 (CAV3) antibodyKD Validated CAV3 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 23GB3035 unconjugated Recombinant Antibody
anti-Caveolin 3 (CAV3) antibodyCAV3 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Caveolin 3 (CAV3) (N-Term) antibodyVerified CAV3 适用: 人, 小鼠, 大鼠, Pig WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Caveolin 3 (CAV3) (AA 5-31), (N-Term) antibodyCAV3 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB19453 unconjugated
anti-Caveolin 3 (CAV3) (AA 1-83) antibodyCAV3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Caveolin 3 (CAV3) (N-Term) antibodyCAV3 适用: 人, 小鼠, 大鼠, Cow, 兔, 马, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Caveolin 3 (CAV3) (AA 1-83) antibodyCAV3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1B9 unconjugated
anti-Caveolin 3 (CAV3) (N-Term) antibodyCAV3 适用: 人, 小鼠, 大鼠, Pig, Cow WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Caveolin 3 (CAV3) (AA 95-151) antibodyCAV3 适用: 人, 小鼠 WB, ELISA, FACS, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
Immunofluorescence, 2 μg/mL
ELISA, 0.1-0.5 μg/mL
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说明
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Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Caveolin 3 (CAV3)
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别名
- CAV3
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背景
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Synonyms: Caveolin-3, M-caveolin, CAV3
Tissue Specificity: Expressed in red blood cells, overexpressed in red blood cells (cytoplasm) of patients with hereditary non- spherocytic hemolytic anemia of unknown etiology. .
Background: Caveolin-3 is a protein that in humans is encoded by the CAV3 gene. This gene encodes a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites.
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分子量
- 22 kDa
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基因ID
- 859
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UniProt
- P56539
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途径
- Carbohydrate Homeostasis, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development, Negative Regulation of Transporter Activity
抗原
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