Caveolin 3 抗体 (AA 1-55)
Quick Overview for Caveolin 3 抗体 (AA 1-55) (ABIN6719285)
抗原
See all Caveolin 3 (CAV3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-55
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原理
- Anti-Caveolin-3/CAV3 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Caveolin-3/CAV3 Antibody Picoband® (ABIN6719285). Tested in ELISA, IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Caveolin-3/CAV3 recombinant protein (Position: M1-D55).
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亚型
- IgG
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anti-Caveolin 3 (CAV3) (N-Term) antibody
Verified CAV3 适用: 人, 小鼠, 大鼠, Pig WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Caveolin 3 (CAV3) antibodyCAV3 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Caveolin 3 (CAV3) (AA 5-31), (N-Term) antibodyCAV3 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB19453 unconjugated
anti-Caveolin 3 (CAV3) (AA 1-83) antibodyCAV3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Caveolin 3 (CAV3) (N-Term) antibodyCAV3 适用: 人, 小鼠, 大鼠, Cow, 兔, 马, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Caveolin 3 (CAV3) (AA 1-83) antibodyCAV3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1B9 unconjugated
anti-Caveolin 3 (CAV3) (N-Term) antibodyCAV3 适用: 人, 小鼠, 大鼠, Pig, Cow WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Caveolin 3 (CAV3) (AA 95-151) antibodyCAV3 适用: 人, 小鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Caveolin 3 (CAV3) antibodyCAV3 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Caveolin 3 (CAV3) (N-Term) antibodyCAV3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
Immunofluorescence, 2 μg/mL
ELISA, 0.1-0.5 μg/mL
1. McNally EM, de Sá Moreira E, Duggan DJ, Bönnemann CG, Lisanti MP, Lidov HG, Vainzof M, Passos-Bueno MR, Hoffman EP, Zatz M, Kunkel LM (August 1998). "Caveolin-3 in muscular dystrophy". Hum Mol Genet. 7 (5): 871-7. 2. Minetti C, Sotgia F, Bruno C, Scartezzini P, Broda P, Bado M, Masetti E, Mazzocco M, Egeo A, Donati MA, Volonte D, Galbiati F, Cordone G, Bricarelli FD, Lisanti MP, Zara F (April 1998). "Mutations in the caveolin-3 gene cause autosomal dominant limb-girdle muscular dystrophy". Nat Genet. 18 (4): 365-8. -
说明
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Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Caveolin 3 (CAV3)
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别名
- CAV3
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背景
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Synonyms: Caveolin-3, M-caveolin, CAV3
Tissue Specificity: Expressed in red blood cells, overexpressed in red blood cells (cytoplasm) of patients with hereditary non- spherocytic hemolytic anemia of unknown etiology. .
Background: Caveolin-3 is a protein that in humans is encoded by the CAV3 gene. This gene encodes a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites.
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分子量
- 22 kDa
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基因ID
- 859
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UniProt
- P56539
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途径
- Carbohydrate Homeostasis, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development, Negative Regulation of Transporter Activity
抗原
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