ACTN3 抗体 (C-Term)
Quick Overview for ACTN3 抗体 (C-Term) (ABIN6719273)
抗原
See all ACTN3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 574-617, C-Term
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原理
- Anti-ACTN3 Antibody Picoband® (monoclonal, 9B5)
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序列
- EADRERGAIM GIQGEIQKIC QTYGLRPCST NPYITLSPQD INT
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-ACTN3 Antibody Picoband® (monoclonal, 9B5) (ABIN6719273). Tested in IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human ACTN3, different from the related mouse sequence by five amino acids.
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亚型
- IgG1
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anti-Actinin, alpha 3 (ACTN3) (N-Term) antibody
ACTN3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 3 (ACTN3) (Center) antibodyACTN3 适用: 人, 小鼠, 大鼠 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 3 (ACTN3) (N-Term) antibodyACTN3 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 3 (ACTN3) (AA 580-630) antibodyACTN3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 3 (ACTN3) antibodyACTN3 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Actinin, alpha 3 (ACTN3) (AA 574-617), (C-Term) antibodyACTN3 适用: 人, 小鼠, 大鼠 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 3 (ACTN3) (N-Term) antibodyACTN3 适用: 人, 小鼠, 大鼠, Cow, 兔, 犬, 豚鼠, 马, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 3 (ACTN3) (AA 162-416) antibodyACTN3 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 3 (ACTN3) (AA 180-229) antibodyACTN3 适用: 人, 小鼠, 大鼠, Cow, 兔, 犬, 豚鼠, 马, Hamster, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 3 (ACTN3) (N-Term) antibodyACTN3 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
1. Papadimitriou ID, Papadopoulos C, Kouvatsi A, Triantaphyllidis C (April 2008). "The ACTN3 gene in elite Greek track and field athletes". Int J Sports Med 29 (4): 352-5. 2. Yang N, MacArthur DG, Gulbin JP, Hahn AG, Beggs AH, Easteal S, North K (September 2003). "ACTN3 genotype is associated with human elite athletic performance". Am. J. Hum. Genet. 73 (3): 627-31. -
说明
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Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- ACTN3 (Actinin, alpha 3 (ACTN3))
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别名
- ACTN3
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背景
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Synonyms: Alpha-actinin-3, Alpha-actinin skeletal muscle isoform 3, F-actin cross-linking protein, ACTN3
Tissue Specificity: Expressed only in a subset of type 2 skeletal muscle fibers.
Background: Alpha-actinin-3, also known as alpha-actinin skeletal muscle isoform 3 or F-actin cross-linking protein, is a protein that in humans is encoded by the ACTN3 gene. This gene encodes a member of the alpha-actin binding protein gene family. The encoded protein is primarily expressed in skeletal muscle and functions as a structural component of sarcomeric Z line. This protein is involved in crosslinking actin containing thin filaments. An allelic polymorphism in this gene results in both coding and non-coding variants, the reference genome represents the coding allele. The non-functional allele of this gene is associated with elite athlete status.
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分子量
- 103 kDa
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基因ID
- 89
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UniProt
- Q08043
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途径
- Cell-Cell Junction Organization
抗原
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