AFT1 抗体 (AA 1-271) (DyLight 550)
Quick Overview for AFT1 抗体 (AA 1-271) (DyLight 550) (ABIN7354644)
抗原
See all AFT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-271
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原理
- Anti-Human ATF1 DyLight® 550 conjugated Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Human ATF1 DyLight® 550 conjugated Antibody -Dyl550. Tested in Flow Cytometry applications. This antibody reacts with Human.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human ATF1 recombinant protein (Position: M1-V271). Human ATF1 shares 91% amino acid (aa) sequence identity with mouse ATF1.
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亚型
- IgG
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anti-Activating Transcription Factor 1 (AFT1) (AA 1-271) antibody
AFT1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 1 (AFT1) (AA 1-271) antibodyAFT1 适用: 人 WB, ELISA, IHC (p), RNAi 宿主: 小鼠 Monoclonal 3E7 unconjugated
anti-Activating Transcription Factor 1 (AFT1) (AA 3-245) antibodyAFT1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 1 (AFT1) (Internal Region) antibodyAFT1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 1 (AFT1) (AA 1-271) antibodyAFT1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Activating Transcription Factor 1 (AFT1) (C-Term) antibodyAFT1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 1 (AFT1) (AA 3-213) antibodyAFT1 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 1 (AFT1) (AA 1-210) antibodyAFT1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 1 (AFT1) (pSer63) antibodyAFT1 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 1 (AFT1) (AA 1-272) antibodyAFT1 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3E7 unconjugated
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应用备注
- Flow Cytometry (Fixed), 1-3 μg/1x106 cells1. ucman, J., Delattre, O., Desmaze, C., Epstein, A. L., Stenman, G., Speleman, F., Fletchers, C. D. M., Aurias, A., Thomas, G. EWS and ATF-1 gene fusion induced by t(12,22) translocation in malignant melanoma of soft parts. Nature Genet. 4: 341-345, 1993. 2. "Entrez Gene: ATF1 activating transcription factor 1"
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说明
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Other applications have not been tested. Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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- AFT1 (Activating Transcription Factor 1 (AFT1))
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别名
- ATF1
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背景
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Synonyms: Cyclic AMP-dependent transcription factor ATF-1, cAMP-dependent transcription factor ATF-1, Activating transcription factor 1, Protein TREB36, ATF1
Background: ATF1, also known as activating transcription factor 1, is a protein that in humans is encoded by the ATF1 gene. It is mapped to 12q13.12. This gene encodes an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. This protein is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases, cAMP-dependent protein kinase A, calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3). Its phosphorylation enhances its transactivation and transcriptional activities, and enhances cell transformation.
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分子量
- 39 kDa
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基因ID
- 466
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UniProt
- P18846
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途径
- Neurotrophin Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades
抗原
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