CCDC90A 抗体
Quick Overview for CCDC90A 抗体 (ABIN6719261)
抗原
See all CCDC90A (MCUR1) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Anti-MCUR1 Antibody Picoband®
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序列
- ATQQAEIIVS ALVKILEANM DIVYKDMVTK MQQE
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-MCUR1 Antibody Picoband® (ABIN6719261). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human MCUR1, which shares 79.4% and 82.3% amino acid (aa) sequence identity with mouse and rat MCUR1, respectively.
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亚型
- IgG
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anti-Mitochondrial Calcium Uniporter Regulator 1 (MCUR1) (Middle Region) antibody
MCUR1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrial Calcium Uniporter Regulator 1 (MCUR1) (AA 261-359) antibodyMCUR1 适用: 人 IF (cc), IF (p), ELISA, IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
1. Chaudhuri, D., Artiga, D. J., Abiria, S. A., Clapham, D. E. Mitochondrial calcium uniporter regulator 1 (MCUR1) regulates the calcium threshold for the mitochondrial permeability transition. Proc. Nat. Acad. Sci. 113: E1872-E1880, 2016. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 5/23/2016. 3. Mallilankaraman, K., Cardenas, C., Doonan, P. J., Chandramoorthy, H. C., Irrinki, K. M., Golenar, T., Csordas, G., Madireddi, P., Yang, J., Muller, M., Miller, R., Kolesar, J. E., Molgo, J., Kaufman, B., Hajnoczky, G., Foskett, J. K., Madesh, M. MCUR1 is an essential component of mitochondrial Ca(2+) uptake that regulates cellular metabolism. Nature Cell Biol. 14: 1336-1343, 2012. Note: Erratum: Nature Cell Biol. 15: 123 only, 2013. Erratum: Nature Cell Biol. 17: 953 only, 2015. -
说明
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Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- CCDC90A (MCUR1) (Mitochondrial Calcium Uniporter Regulator 1 (MCUR1))
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别名
- MCUR1
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背景
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Synonyms: Mitochondrial calcium uniporter regulator 1, MCU regulator 1, Coiled-coil domain-containing protein 90A, mitochondrial, MCUR1, C6orf79, CCDC90A
Tissue Specificity: Ubiquitously expressed.
Background: MCUR1 is an inner mitochondrial membrane protein that has been shown to function as a component of the mitochondrial Ca (2+) uniporter, in the assembly of mitochondrial respiratory complex IV, and in mitochondrial permeability transition (MPT). The MCUR1 gene is mapped to chromosome 6p23 based on an alignment of the MCUR1 sequence with the genomic sequence.
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分子量
- 40 kDa
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基因ID
- 63933
抗原
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