PIWIL1 抗体 (AA 551-650) (Cy3)
Quick Overview for PIWIL1 抗体 (AA 551-650) (Cy3) (ABIN671634)
抗原
See all PIWIL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 551-650
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交叉反应
- 人, 小鼠
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预测反应
- Rat,Chicken
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from chicken PIWIL1
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- PIWIL1 (Piwi-Like 1 (PIWIL1))
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别名
- PIWIL1
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背景
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Synonyms: PIWI, Piwi-like protein 1, PIWIL1
Background: Plays a central role during gametogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Directly binds methylated piRNAs, a class of 24 to 3 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. Besides their function in transposable elements repression, piRNAs are probably involved in other processes during meiosis such as translation regulation (By similarity).
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基因ID
- 416804
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UniProt
- A6N7Y9
抗原
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