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CD68 抗体 (AA 21-120)

Name: CD68 抗体 (AA 21-120)
SKU: ABIN671406
Availability: OutOfStock

This anti-CD68 antibody is a 兔多克隆 antibody detecting CD68 in ELISA, IHC (p), ICC, IF (p) 和 IF (cc). Suitable for 人, 小鼠和大鼠. This Primary Antibody has been cited in 20+ publications.

A549 cell lysates probed with Anti-CD68 Polyclonal Antibody, Unconjugated at 1:5000 for 90 min at 37˚C. (CD68 抗体 (AA 21-120))

Formalin-fixed and rat colitis tissue labeled with Anti-CD68 Polyclonal Antibody, Unconjugated (ABIN671406) at 1:200 followed by conjugation to the secondary antibody, Goat Anti-Rabbit IgG, Cy5 conjugated, (CD68 抗体 (AA 21-120))

Formalin-fixed and paraffin embedded rat myocardium labeled with Anti-MuRF1/Trim63 Polyclonal Antibody, Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining. (CD68 抗体 (AA 21-120))

IHC (p)

3 images

(20 references)

产品编号 ABIN671406

发货至: 中国

Quick Overview for CD68 抗体 (AA 21-120) (ABIN671406)

抗原

See all CD68 抗体

CD68 (CD68 Molecule (CD68))

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This CD68 antibody is un-conjugated

应用范围

ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Discover our top product CD68 Primary Antibody

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AA 21-120

交叉反应

人, 小鼠, 大鼠

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from mouse CD68

亚型

IgG
anti-CD68 Molecule (CD68) (AA 312-326), (Middle Region) antibody
CD68 适用: 小鼠, 大鼠 FACS, IHC, WB, IF 宿主: 兔 Polyclonal unconjugated

anti-CD68 Molecule (CD68) (AA 42-155) antibody
CD68 适用: 人 FACS, IHC, WB, ELISA, ICC 宿主: 小鼠 Monoclonal 3F7D3 unconjugated

anti-CD68 Molecule (CD68) antibody
CD68 适用: 人, 小鼠, 猴, 大鼠 FACS, IHC, WB, IF, ISt, StM 宿主: 小鼠 Monoclonal C68-684 unconjugated

anti-CD68 Molecule (CD68) (AA 150-301) antibody
CD68 适用: 人 FACS, IHC, ELISA, ISt, StM, Coat 宿主: 小鼠 Monoclonal LAMP4-1830 unconjugated

anti-CD68 Molecule (CD68) antibody
CD68 适用: 人 FACS, IHC, WB, IF, ISt, StM 宿主: 小鼠 Monoclonal rLAMP4-824 unconjugated Recombinant Antibody

anti-CD68 Molecule (CD68) (AA 150-221) antibody
CD68 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal C68-2709 unconjugated

anti-CD68 Molecule (CD68) antibody (PE)
CD68 适用: 人 FACS 宿主: 小鼠 Monoclonal Y1-82A PE

anti-CD68 Molecule (CD68) (AA 22-319) antibody
CD68 适用: 人 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated

anti-CD68 Molecule (CD68) (AA 341-354), (C-Term) antibody
CD68 适用: 人 IHC, WB 宿主: 兔 Polyclonal unconjugated

anti-CD68 Molecule (CD68) (AA 1-130) antibody
CD68 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Guo, Jin, Jin, Chen, Lei, Wang: "Radical polymerization-crosslinking method for improving extracellular matrix stability in bioprosthetic heart valves with reduced potential for calcification and inflammatory response." in: Acta biomaterialia, Vol. 82, pp. 44-55, (2019) (PubMed).

Zhao, Yin, Fang, Xu, Sun, Xu, Liu, Peng: "Protective effects of dioscin against systemic inflammatory response syndromevia adjusting TLR2/MyD88/NF‑κb signal pathway." in: International immunopharmacology, Vol. 65, pp. 458-469, (2019) (PubMed).

Nishizawa, Iguchi, Fukuoka, Takahashi, Suda, Bando, Matsumoto, Yoshida, Odake, Ogawa, Takahashi: "IGF-I induces senescence of hepatic stellate cells and limits fibrosis in a p53-dependent manner." in: Scientific reports, Vol. 6, pp. 34605, (2018) (PubMed).

Ganguly, Sahu, Ohanyan, Haney, Chavez, Shah, Yalamanchili, Raman: "Oral chromium picolinate impedes hyperglycemia-induced atherosclerosis and inhibits proatherogenic protein TSP-1 expression in STZ-induced type 1 diabetic ApoE(-/-) mice." in: Scientific reports, Vol. 7, pp. 45279, (2017) (PubMed).

Kugo, Zaima, Onozato, Miyamoto, Hashimoto, Yanagimoto, Moriyama: "Suppressive effects of dietary EPA-rich fish oil on the degradation of elastin fibers in the aortic wall in nicotine-administered mice." in: Food & function, Vol. 8, Issue 8, pp. 2829-2835, (2017) (PubMed).

Vendrov, Stevenson, Alahari, Pan, Wickline, Madamanchi, Runge: "Attenuated Superoxide Dismutase 2 Activity Induces Atherosclerotic Plaque Instability During Aging in Hyperlipidemic Mice." in: Journal of the American Heart Association, Vol. 6, Issue 11, (2017) (PubMed).

Müller, Vogl, Pappritz, Miteva, Savvatis, Rohde, Most, Lassner, Pieske, Kühl, Van Linthout, Tschöpe: "Pathogenic Role of the Damage-Associated Molecular Patterns S100A8 and S100A9 in Coxsackievirus B3-Induced Myocarditis." in: Circulation. Heart failure, Vol. 10, Issue 11, (2017) (PubMed).

Xu, Yuan, Li, Dewey, Li, Zhang: "Lysosomal cholesterol accumulation in macrophages leading to coronary atherosclerosis in CD38(-/-) mice." in: Journal of cellular and molecular medicine, Vol. 20, Issue 6, pp. 1001-13, (2016) (PubMed).

Kang, Kim, Joung, Lee, You, Choi, Ryu, Ko, Lee, Lee, Ku, Shong, Lee, Kim: "The Roles of Adipokines, Proinflammatory Cytokines, and Adipose Tissue Macrophages in Obesity-Associated Insulin Resistance in Modest Obesity and Early Metabolic Dysfunction." in: PLoS ONE, Vol. 11, Issue 4, pp. e0154003, (2016) (PubMed).

Xu, Zhang, Halquist, Yuan, Henderson, Dewey, Li, Li, Zhang: "Simvastatin promotes NPC1-mediated free cholesterol efflux from lysosomes through CYP7A1/LXRα signalling pathway in oxLDL-loaded macrophages." in: Journal of cellular and molecular medicine, (2016) (PubMed).

Bang, Seo, Seo, Jo, Jung, Yu, Park, Park: "Bacillus subtilis KCTC 11782BP-Produced Alginate Oligosaccharide Effectively Suppresses Asthma via T-Helper Cell Type 2-Related Cytokines." in: PLoS ONE, Vol. 10, Issue 2, pp. e0117524, (2015) (PubMed).

Shang, Bai, Wang, Song, Guo, Zhang, Wang: "Delivery of Adipose-Derived Stem Cells Attenuates Adipose Tissue Inflammation and Insulin Resistance in Obese Mice Through Remodeling Macrophage Phenotypes." in: Stem cells and development, Vol. 24, Issue 17, pp. 2052-64, (2015) (PubMed).

Hong, Lee, Ko, Park, Park, Choi, Yoon, Ahn, Park, Woo, Oh: "Neonatal systemic inflammation in rats alters retinal vessel development and simulates pathologic features of retinopathy of prematurity." in: Journal of neuroinflammation, Vol. 11, pp. 87, (2014) (PubMed).

Wang, Hu, Wang, Gu, Gao, Cao, Zheng: "5-Aminolevulinic acid-mediated sonodynamic therapy reverses macrophage and dendritic cell passivity in murine melanoma xenografts." in: Ultrasound in medicine & biology, Vol. 40, Issue 9, pp. 2125-33, (2014) (PubMed).

Savvatis, Müller, Fröhlich, Pappritz, Zietsch, Hamdani, Grote, Schieffer, Klingel, Van Linthout, Linke, Schultheiss, Tschöpe: "Interleukin-6 receptor inhibition modulates the immune reaction and restores titin phosphorylation in experimental myocarditis." in: Basic research in cardiology, Vol. 109, Issue 6, pp. 449, (2014) (PubMed).

Xiao, Zou, Yang, Rehman, Ansari, Yuan, Zhou, Cui, Peng, Song: "The role of visfatin on the regulation of inflammation and apoptosis in the spleen of LPS-treated rats." in: Cell and tissue research, (2014) (PubMed).

Wang, Dong, Liu, Song, Song, Shang, Jiang, Guo, Zhang: "Programmed cell death-4 deficiency prevents diet-induced obesity, adipose tissue inflammation, and insulin resistance." in: Diabetes, Vol. 62, Issue 12, pp. 4132-43, (2014) (PubMed).

Zeng, Zhang, Li, Yang, Chen, Liu: "A new method to isolate and culture rat kupffer cells." in: PLoS ONE, Vol. 8, Issue 8, pp. e70832, (2013) (PubMed).

Chen, Bai, Liao, Peng, Wu, Wang, Zeng, Xie: "Electrospun poly(L-lactide)/poly(?-caprolactone) blend nanofibrous scaffold: characterization and biocompatibility with human adipose-derived stem cells." in: PLoS ONE, Vol. 8, Issue 8, pp. e71265, (2013) (PubMed).

Wu, Wu, Wu, Zhao, Li, Varghese, Moorhead, Powis, Chen, Ruan: "Chronic inflammation exacerbates glucose metabolism disorders in C57BL/6J mice fed with high-fat diet." in: The Journal of endocrinology, Vol. 219, Issue 3, pp. 195-204, (2013) (PubMed).

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抗原

CD68 (CD68 Molecule (CD68))

别名

CD68

背景

Synonyms: Lamp4, gp11, Scard1, Macrosialin, CD68
Background: Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.

基因ID

12514

UniProt

P31996