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CDK5 抗体 (AA 15-100)

Name: CDK5 抗体 (AA 15-100)
SKU: ABIN670101
Availability: OutOfStock

This anti-CDK5 antibody is a 兔多克隆 antibody detecting CDK5 in WB, FACS, IF (cc), IF (p), IHC (p) 和 IHC (fro). Suitable for 人, 小鼠和大鼠. This Primary Antibody has been cited in 3+ publications.

Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti-CDK5 Polyclonal Antibody (ABIN670101) at 1:200 followed by conjugation to the secondary antibody and DAB staining. (CDK5 抗体 (AA 15-100))

IHC

Formalin-fixed and paraffin-embedded rat brain labeled with Anti-CDK5 Polyclonal Antibody, Unconjugated (ABIN670101) 1:200, overnight at 4°C, The secondary antibody was Goat Anti-Rabbit IgG, Cy3 conjugated used at 1:200 dilution for 40 minutes at 37°C. (CDK5 抗体 (AA 15-100))

Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti-CDK5 Polyclonal Antibody at 1:200 followed by conjugation to the secondary antibody and DAB staining. (CDK5 抗体 (AA 15-100))

IHC (p)

3 images

(3 references)

产品编号 ABIN670101

发货至: 中国

Datasheet as PDF

Quick Overview for CDK5 抗体 (AA 15-100) (ABIN670101)

抗原

See all CDK5 抗体

CDK5 (Cyclin-Dependent Kinase 5 (CDK5))

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This CDK5 antibody is un-conjugated

应用范围

Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Discover our top product CDK5 Primary Antibody

抗原表位
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AA 15-100

特异性

This antibody will detect both isoform variants of this protein. Due to similar amino acid composition of this protein to CDK3 in human, there is a chance that this antibody will react with CDK3 in human, based on an 83 % sequence similarity.

交叉反应

人, 小鼠, 大鼠

预测反应

Cow,Pig

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human CDK5

亚型

IgG
anti-Cyclin-Dependent Kinase 5 (CDK5) antibody
CDK5 适用: 人, 大鼠, 猴 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 4E4 unconjugated

anti-Cyclin-Dependent Kinase 5 (CDK5) (AA 1-292) antibody
CDK5 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated

anti-Cyclin-Dependent Kinase 5 (CDK5) (AA 1-292) antibody
CDK5 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Cyclin-Dependent Kinase 5 (CDK5) antibody
CDK5 适用: 人, 小鼠 WB, FACS, IF, IHC (p) 宿主: 小鼠 Monoclonal 1552CT262-105-8 unconjugated

anti-Cyclin-Dependent Kinase 5 (CDK5) (AA 1-292) antibody
CDK5 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Cyclin-Dependent Kinase 5 (CDK5) (AA 254-289) antibody
CDK5 适用: 人, 小鼠 WB, ELISA, FACS, IF 宿主: 兔 Polyclonal unconjugated

anti-Cyclin-Dependent Kinase 5 (CDK5) (Tyr15) antibody
CDK5 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Cyclin-Dependent Kinase 5 (CDK5) (AA 254-289), (C-Term) antibody
CDK5 适用: 人, 小鼠 WB, FACS, IF 宿主: 兔 Polyclonal RB50850 unconjugated

anti-Cyclin-Dependent Kinase 5 (CDK5) (AA 1-292) antibody
CDK5 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

anti-Cyclin-Dependent Kinase 5 (CDK5) (AA 195-292) antibody
CDK5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A2 unconjugated

应用备注

WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Cao, Jia, Wei, Liu, Liu, Li: "Traditional Chinese Medicine Huannao Yicong Decoction Extract Decreases Tau Hyperphosphorylation in the Brain of Alzheimer's Disease Model Rats Induced by Aβ1-42." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2016, pp. 6840432, (2016) (PubMed).

Yin, Qi, Ren, Wang, Jiang, Feng, Cui: "Roscovitine treatment caused impairment of fertilizing ability in mice." in: Toxicology letters, Vol. 237, Issue 3, pp. 200-9, (2015) (PubMed).

Li, Wang, Guo, Huang, Zhao, Zhu, Ma, Liang, Zhang, Huang, Wan: "Protective effect of Xingnaojia formulation on rats with brain and liver damage caused by chronic alcoholism." in: Experimental and therapeutic medicine, Vol. 10, Issue 5, pp. 1643-1652, (2015) (PubMed).
抗原

CDK5 (Cyclin-Dependent Kinase 5 (CDK5))

别名

CDK5

背景

Synonyms: PSSALRE, Cyclin-dependent-like kinase 5, Cell division protein kinase 5, Serine/threonine-protein kinase PSSALRE, Tau protein kinase II catalytic subunit, TPKII catalytic subunit, CDK5, CDKN5
Background: CDK5 is serine/threonine kinase involved in synaptic regulation and neuronal development, phosphorylates synaptic protein Pctaire1, regulates acetylcholine receptor expression.CDK5 is a member of the cyclindependent kinase family of serine/threonine kinases. It is present in numerous mammalian tissues including kidney, testes, and ovary. Its activity is detected almost exclusively in brain extracts. Neuronal and muscle cells contain the highest amount of this protein. Similar to other Cdks, monomeric Cdk5 displays no enzymatic activity, but Cdk5 is not activated by cyclins. Instead, the p35 protein, which is expressed solely in the brain, activates Cdk5. Cdk5 interacts with D1 and D3 type G1 cyclins and can phosphorylate histone H1, TAU, MAP2 and NF-H and NF-M. Cdk5 activity is involved in terminal differentiation of neurons and muscle cells.

基因ID

1020

UniProt

Q00535

途径

Cell Division Cycle, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of Cell Size, Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis