EMP1 抗体 (AA 101-160)
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北京 101111
Quick Overview for EMP1 抗体 (AA 101-160) (ABIN670086)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 101-160
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原理
- EMP-1 Polyclonal Antibody
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from mouse Emp1
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亚型
- IgG
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anti-Epithelial Membrane Protein 1 (EMP1) (AA 22-66) antibody
EMP1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Epithelial Membrane Protein 1 (EMP1) (AA 1-157) antibodyEMP1 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Epithelial Membrane Protein 1 (EMP1) (AA 35-63), (N-Term) antibodyEMP1 适用: 人 WB 宿主: 兔 Polyclonal RB36582 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- EMP1 (Epithelial Membrane Protein 1 (EMP1))
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别名
- EMP1
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背景
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Synonyms: TMP, I-8-9, Epithelial membrane protein 1, EMP-1, Tumor-associated membrane protein, Emp1
Background: Epithelial membrane protein-1 (EMP-1) is a four pass transmembrane protein consisting of 160 amino acids. It is a member of a small family of epithelial membrane proteins. EMP-1 is very similar in structure to its close relative, Peripheral Myelin Protein 22 (PMP22). It is most predominantly expressed in tissues of the gastrointestinal tract but has also been found to be a junctional protein in the liver expressed along the intercellular border. EMP-1 directly interacts with the C-terminus of the P2X7 receptor and may be involved in membrane blebbing. EMP-1 may also be an important regulator in cell communication, signaling, and adhesion. When EMP-1 is overexpressed, cell proliferation is inhibited, S phase is arrested and G1 phase is prolonged in esophogeal cancer cells. EMP-1 may play a role in tumorigenesis and has been identified as a biomarker for gefitinib treatment resistance for patients with lung cancer.
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基因ID
- 13730
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UniProt
- P47801
抗原
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