TUBB3 抗体
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- 抗原 See all TUBB3 抗体
- TUBB3 (Tubulin, beta 3 (TUBB3))
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适用
- 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TUBB3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- Supplier Product No.
- 212-301-e55
- Supplier
- Rockland
- 原理
- Tubulin beta 3 Antibody
- 交叉反应 (详细)
- Anti-Tubulin beta 3 Antibody is directed against rat Tubulin beta III protein.
- 纯化方法
- The antibody was Protein G purified from cell culture supernatant.
- 免疫原
- Anti-Tubulin beta 3 Monoclonal Antibody was produced by repeated immunizations with a synthetic peptide corresponding to amino acid residues specific to beta III tubulin.
- 克隆位点
- AA10
- 亚型
- IgG
- Top Product
- Discover our top product TUBB3 Primary Antibody
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- 应用备注
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Immunohistochemistry_Dilution: 1:1,000
Western_Blot_Dilution: 1:10,000
Other: User Optimized
- 说明
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Anti-Tubulin beta 3 (Mouse) antibody is tested for use in Western Blotting and IHC. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 55 kDa in size corresponding to beta III tubulin proteins in the appropriate cell lysate or extract.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
- 有效期
- 12 months
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- 抗原
- TUBB3 (Tubulin, beta 3 (TUBB3))
- 别名
- Tubulin beta 3 (TUBB3 产品)
- 背景
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Synonyms: mouse anti-Tubulin beta 3 Antibody, Neuron-specific class III beta-tubulin, Tubulin beta-3 chain, Tubulin beta-4 chain, Tubulin beta-III
Background: Tubulin beta 3 Antibody detects Tubulin beta III protein. Tubulin is the major constituent of microtubules, existing as a heterodimer of the α and β subunits. The beta III isoform of tubulin is found almost exclusively in neuronal processes of adult tissues and is therefore an excellent marker for neurons. Neuron specific, posttranslational modifications within the C-terminal domain of beta III tubulin have been shown to be developmentally regulated suggesting that they may serve to modulate the interaction of tubulin with microtubule associated proteins. Additionally, beta III tubulin has been found to be highly expressed in cancer cells such as small cell lung cancer, large cell neuroendocrine carcinoma and adenocarcinomas and is correlated with an increasing histological degree of malignancy.
Gene Name: TUBB3
- 基因ID
- 246118
- UniProt
- Q4QRB4
- 途径
- Microtubule Dynamics, M Phase
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