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Thrombomodulin 抗体

The 兔 多克隆 anti-Thrombomodulin antibody (ABIN669636) specifically detects Thrombomodulin in WB, IHC (p) 和 IF (p). The antibody is reactive with 人, 小鼠, 大鼠, 犬 和 Cow samples.
产品编号 ABIN669636
发货至: 中国
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Quick Overview for Thrombomodulin 抗体 (ABIN669636)

抗原

See all Thrombomodulin (THBD) 抗体
Thrombomodulin (THBD)

适用

人, 小鼠, 大鼠, 犬, Cow

宿主

  • 97
  • 63
  • 8
  • 2

克隆类型

  • 106
  • 63
  • 1
多克隆

标记

  • 75
  • 21
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Thrombomodulin antibody is un-conjugated

应用范围

  • 111
  • 84
  • 58
  • 49
  • 38
  • 28
  • 27
  • 22
  • 21
  • 14
  • 13
  • 11
  • 10
  • 5
  • 5
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 交叉反应

    Cow, 犬, 人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from mouse Thrombomodulin

    亚型

    IgG
  • 应用备注

    WB(1:100-500)
    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    Thrombomodulin (THBD)

    别名

    Thrombomodulin

    背景

    Synonyms: Thrombomodulin, CD 141, CD141, CD141 antigen, Fetomodulin, THBD, THRM, TM, AHUS 6, AHUS6, BDCA 3, BDCA3, THPH12, TRBM_HUMAN.

    Background: Thrombomodulin, TM is cell surface glycoprotein, plays an important role in the protein C anticoagulant pathway. It located in a vein, artery and capillary endothelial cells on the surface of plasma membrane protein. It is generally believed: TM vascular endothelial injury is an important parameter is the thrombin receptor, known in a variety of normal human tissues, can also be expressed in many tumors, TM may be similar to the E-cadherin,and is a lectin Like activity of a new class of members of the cell adhesion molecules.CD141/Thrombomodulin is an exclusively endothelial cell surface glycoprotein that forms a 1:1 complex with thrombin. Binding of thrombin to this high-affinity receptor alters its specificity toward several substrates. The complex activates protein C approximately 1000 times faster than thrombin alone. Activated protein C degrades clotting factors V and VIII, thus, thrombomodulin converts thrombin into a physiologic anticoagulant. Thrombomodulin is also found in the circulatory and urinary systems, the physiologic significance of this is obscure.

    分子量

    61kDa

    基因ID

    21824
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