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SOX2 抗体 (AA 227-317)

Name: SOX2 抗体 (AA 227-317)
SKU: ABIN669621
Availability: OutOfStock

This anti-SOX2 antibody is a 兔多克隆 antibody detecting SOX2 in WB, ELISA, FACS, ICC, IHC (p), IF (cc), IF (p) 和 IHC (fro). Suitable for 人, 小鼠, 大鼠和山羊. This Primary Antibody has been cited in 8+ publications.

Formalin-fixed and paraffin embedded human stomach labeled with Anti-SOX2 Polyclonal Antibody, Unconjugated (ABIN669621) at 1:200 followed by conjugation to the secondary antibody and DAB staining (SOX2 抗体 (AA 227-317))

IHC

Lane 1: mouse embryo lysates Lane 2: mouse lung lysates probed with Anti SOX2 Polyclonal Antibody, Unconjugated (ABIN669621) at 1:200 in 4 °C. (SOX2 抗体 (AA 227-317))

SDS

Formalin-fixed and paraffin embedded rat esophagus labeled with Anti-SOX2 Polyclonal Antibody, Unconjugated (ABIN669621) at 1:200 followed by conjugation to the secondary antibody and DAB staining (SOX2 抗体 (AA 227-317))

IHC

NCCIT cells probed with Rabbit Anti-SOX2 Polyclonal Antibody Alexa Fluor 488 Conjugated Secondary Antibody. (SOX2 抗体 (AA 227-317))

FACS

Formalin-fixed and paraffin embedded human stomach labeled with Anti-SOX2 Polyclonal Antibody, Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining (SOX2 抗体 (AA 227-317))

IHC (p)

Formalin-fixed and paraffin embedded rat esophagus labeled with Anti-SOX2 Polyclonal Antibody, Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining (SOX2 抗体 (AA 227-317))

IHC (p)

6 images

(8 references)

产品编号 ABIN669621

发货至: 中国

Datasheet as PDF

Quick Overview for SOX2 抗体 (AA 227-317) (ABIN669621)

抗原

See all SOX2 抗体

SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

适用

人, 小鼠, 大鼠, 山羊

宿主

兔

克隆类型

多克隆

标记

This SOX2 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Discover our top product SOX2 Primary Antibody

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AA 227-317

交叉反应

山羊, 人, 小鼠, 大鼠

预测反应

Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from mouse Transcription factor SOX-2

亚型

IgG
anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) antibody
KO Validated SOX2 适用: 人 WB, IF, FACS, ICC, IHC (p), IP, IHC (fro), CUT&RUN 宿主: 兔 Polyclonal unconjugated

anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 1-140) antibody
SOX2 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 1-317) antibody
SOX2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 176-305) antibody
SOX2 适用: 人, 小鼠 WB, ELISA, IHC, Coat, StM 宿主: 小鼠 Monoclonal SOX2-1791 unconjugated

anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (N-Term) antibody
SOX2 适用: 人, 小鼠, 大鼠, 山羊, Cow, Pig, 绵羊, 斑马鱼, 马, 兔, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) antibody
SOX2 适用: 人 ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 10F10 unconjugated

anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 89-119), (N-Term) antibody
SOX2 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB14026 unconjugated

anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (Middle Region) antibody
SOX2 适用: 人, 小鼠, 大鼠, 山羊, Cow, 绵羊, 斑马鱼, 马, 兔, 犬, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 89-119) antibody
SOX2 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated

anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 251-284) antibody
SOX2 适用: 人 WB, IF, FACS 宿主: 兔 Polyclonal RB14259 unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Wang, Wang, Li, Liu, Jiang, Li, Cao, Zhao, Wang, Luo: "Silencing stem cell factor attenuates stemness and inhibits migration of cancer stem cells derived from Lewis lung carcinoma cells." in: Tumour biology, Vol. 37, Issue 6, pp. 7213-27, (2016) (PubMed).

Yan, Li, Li, Lin, Yang: "Osthole Protects Bone Marrow-Derived Neural Stem Cells from Oxidative Damage through PI3K/Akt-1 Pathway." in: Neurochemical research, (2016) (PubMed).

Ma, Zhou, Li, Zheng, Wu, Niu, Tang, He, Li, Hua: "Lin28a promotes self-renewal and proliferation of dairy goat spermatogonial stem cells (SSCs) through regulation of mTOR and PI3K/AKT." in: Scientific reports, Vol. 6, pp. 38805, (2016) (PubMed).

Liu, Zhang, Wang, Yang, Tan: "JNK is required for maintaining the tumor-initiating cell-like properties of acquired chemoresistant human cancer cells." in: Acta pharmacologica Sinica, Vol. 36, Issue 9, pp. 1099-106, (2016) (PubMed).

Liu, Jiang, Wang, Hao, Shang, Zhang, Cao, Xu, Zhan, Wang: "A panel of protein markers for the early detection of lung cancer with bronchial brushing specimens." in: Cancer cytopathology, Vol. 122, Issue 11, pp. 833-41, (2014) (PubMed).

Vadasz, Jensen, Moncada, Girard, Zhang, Blanchette, Finck: "Second and third trimester amniotic fluid mesenchymal stem cells can repopulate a de-cellularized lung scaffold and express lung markers." in: Journal of pediatric surgery, Vol. 49, Issue 11, pp. 1554-63, (2014) (PubMed).

Liu, Li, Liu, Sui, Liu, Xiao, Zheng, Chen, Yao, Xing, Zhou, Li: "A signature for induced pluripotent stem cell-associated genes in colorectal cancer." in: Medical oncology (Northwood, London, England), Vol. 30, Issue 1, pp. 426, (2013) (PubMed).

Gao, Zhao, Song, Yang: "Expression pattern of embryonic stem cell markers in DFAT cells and ADSCs." in: Molecular biology reports, Vol. 39, Issue 5, pp. 5791-804, (2012) (PubMed).
抗原

SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

别名

SOX2

背景

Synonyms: lcc, ysb, Sox-2, Transcription factor SOX-2, Sox2
Background: Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP26. Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).

基因ID

20674

UniProt

P48432

途径

Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis