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DNMT3A 抗体 (AA 26-100)

Name: DNMT3A 抗体 (AA 26-100)
SKU: ABIN669336
Availability: OutOfStock

Cited in 2+ publications. This anti-DNMT3A antibody is a 兔多克隆 antibody detecting DNMT3A in FACS, IF (cc), IF (p), IHC (p) 和 IHC (fro). Suitable for 人, 小鼠和大鼠.

Formalin-fixed and paraffin embedded human gastric carcinoma labeled with Anti-Dnmt3a Polyclonal Antibody, Unconjugated at 1:200, followed by conjugation to the secondary antibody and DAB staining (DNMT3A 抗体 (AA 26-100))

IHC (p)

Formalin-fixed and paraffin embedded human gastric carcinoma labeled with Anti-Dnmt3a Polyclonal Antibody, Unconjugated (ABIN669336) at 1:200, followed by conjugation to the secondary antibody and DAB staining (DNMT3A 抗体 (AA 26-100))

IHC

Formalin-fixed and paraffin embedded human breast carcinoma labeled with Anti-Dnmt3a Polyclonal Antibody, Unconjugated (ABIN669336) at 1:200, followed by conjugation to the secondary antibody and DAB staining (DNMT3A 抗体 (AA 26-100))

IHC

Image provided by One World Lab validation program. (DNMT3A 抗体 (AA 26-100))

IF (cc)

4 images

(2 references)

产品编号 ABIN669336

发货至: 中国

Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111

No. 88 KeChuang 6th Street

Beijing Economic Technological Development Area

Room 801-803

4A Biotech Co.,Ltd.

Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for DNMT3A 抗体 (AA 26-100) (ABIN669336)

抗原

See all DNMT3A 抗体

DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This DNMT3A antibody is un-conjugated

应用范围

Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Discover our top product DNMT3A Primary Antibody

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AA 26-100

交叉反应

人, 小鼠, 大鼠

预测反应

Cow

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human Dnmt3a

亚型

IgG
anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 500-700) antibody
DNMT3A 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 457-486) antibody
DNMT3A 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB01852 unconjugated

anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 46-180) antibody
DNMT3A 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 4G5F11 unconjugated

anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (2meLys44) antibody
DNMT3A 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated

anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 457-486) antibody
DNMT3A 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 1-912) antibody
DNMT3A 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 680-902) antibody
DNMT3A 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) antibody
KO Validated DNMT3A 适用: 人 WB, IP 宿主: 兔 Monoclonal unconjugated

anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) antibody
DNMT3A 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB2230 unconjugated Recombinant Antibody

anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) antibody
DNMT3A 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 24GB7245 unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Wu, Bu, Yu, Li, Huang, Meng, Zhang, Ma, Li: "Methylation of Septin9 mediated by DNMT3a enhances hepatic stellate cells activation and liver fibrogenesis." in: Toxicology and applied pharmacology, Vol. 315, pp. 35-49, (2016) (PubMed).

Zhao, Hou, Chen, Shao, Zhu, Bu, Gu, Li, Zhang, Du, Fu, Kong, Luo, Long, Li, Deng, Zhao, Cen: "Prenatal cocaine exposure impairs cognitive function of progeny via insulin growth factor II epigenetic regulation." in: Neurobiology of disease, Vol. 82, pp. 54-65, (2015) (PubMed).
抗原

DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))

别名

Dnmt3a

背景

Synonyms: TBRS, DNMT3A2, M.HsaIIIA, DNA (cytosine-5)-methyltransferase 3A, Dnmt3a, DNA methyltransferase HsaIIIA, DNA MTase HsaIIIA
Background: Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. It modifies DNA in a non-processive manner and also methylates non-CpG sites. May preferentially methylate DNA linker between 2 nucleosomal cores and is inhibited by histone H1. Plays a role in paternal and maternal imprinting. Required for methylation of most imprinted loci in germ cells. Acts as a transcriptional corepressor for ZBTB18. Recruited to trimethylated 'Lys-36' of histone H3 (H3K36me3) sites. Can actively repress transcription through the recruitment of HDAC activity.

基因ID

1788

UniProt

Q9Y6K1