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ITGB1 抗体 (PE-Cy5)

This anti-ITGB1 antibody is a 兔 多克隆 antibody detecting ITGB1 in WB 和 FACS. Suitable for 人, 小鼠, 大鼠, Pig, 犬, Cow 和 小鸡.
产品编号 ABIN669228
发货至: 中国

Quick Overview for ITGB1 抗体 (PE-Cy5) (ABIN669228)

抗原

See all ITGB1 抗体
ITGB1 (Integrin beta 1 (ITGB1))

适用

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人, 小鼠, 大鼠, Pig, 犬, Cow, 小鸡

宿主

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克隆类型

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多克隆

标记

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This ITGB1 antibody is conjugated to PE-Cy5

应用范围

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Western Blotting (WB), Flow Cytometry (FACS)
  • 交叉反应

    人, 小鼠, 兔, 大鼠, 绵羊

    预测反应

    Dog,Cow,Pig,Horse,Chicken

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Integrin beta 1

    亚型

    IgG
  • 应用备注

    WB(1:100-500)
    FCM(1:100-500)
    IHC-P(1:100-500)
    IF(IHC-P)(1:100-500)

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    ITGB1 (Integrin beta 1 (ITGB1))

    别名

    Integrin beta 1

    背景

    Synonyms: CD29, FNRB, MDF2, VLAB, GPIIA, MSK12, VLA-BETA, Integrin beta-1, Fibronectin receptor subunit beta, Glycoprotein IIa, VLA-4 subunit beta, ITGB1

    Background: Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha-4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha-11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha-4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin alpha-1/beta-1, alpha-2/beta-1, alpha-6/beta-1 and alpha-7/beta-1 are receptors for lamimin. Integrin alpha-4/beta-1 is a receptor for VCAM1. It recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin. Integrin alpha-3/beta-1 is a receptor for epiligrin, thrombospondin and CSPG4. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. Integrin alpha-V/beta-1 is a receptor for vitronectin. Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands. Isoform beta-1B interferes with isoform beta-1A resulting in a dominant negative effect on cell adhesion and migration (in vitro). In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.

    分子量

    88kDa

    基因ID

    3688

    UniProt

    P05556

    途径

    Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interactome
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