TXN 抗体 (AA 51-105)
Quick Overview for TXN 抗体 (AA 51-105) (ABIN668871)
抗原
See all TXN 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 51-105
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Dog,Cow,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Thioredoxin
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亚型
- IgG
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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: "Screening and identification of post-traumatic stress-related serum factors in children with Wilms' tumors." in: Oncology letters, Vol. 11, Issue 2, pp. 1299-1304, (2016) (PubMed).
: "Cytotoxicity and therapeutic effect of irinotecan combined with selenium nanoparticles." in: Biomaterials, Vol. 35, Issue 31, pp. 8854-66, (2014) (PubMed).
: "First characterization of a teleost Epstein-Barr virus-induced gene 3 (EBI3) reveals a regulatory effect of EBI3 on the innate immune response of peripheral blood leukocytes." in: Developmental and comparative immunology, Vol. 41, Issue 4, pp. 514-22, (2013) (PubMed).
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: "Screening and identification of post-traumatic stress-related serum factors in children with Wilms' tumors." in: Oncology letters, Vol. 11, Issue 2, pp. 1299-1304, (2016) (PubMed).
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- TXN (Thioredoxin (TXN))
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别名
- Thioredoxin
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背景
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Synonyms: TRX, TRDX, TRX1, Thioredoxin, ATL-derived factor, ADF, Surface-associated sulphydryl protein, SASP, TXN
Background: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity. ADF augments the expression of the interleukin-2 receptor TAC (IL2R/P55).
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基因ID
- 7295
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UniProt
- P10599
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途径
- Carbohydrate Homeostasis, Cell RedoxHomeostasis
抗原
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