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Factor VIII 抗体 (AA 401-500) (Cy3)

This anti-Factor VIII antibody is a 兔 多克隆 antibody detecting Factor VIII in IF (p) 和 IF (cc). Suitable for 人, 小鼠, 大鼠 和 兔.
产品编号 ABIN668604
发货至: 中国

Quick Overview for Factor VIII 抗体 (AA 401-500) (Cy3) (ABIN668604)

抗原

See all Factor VIII (F8) 抗体
Factor VIII (F8) (Coagulation Factor VIII (F8))

适用

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  • 61
  • 30
  • 17
  • 11
  • 6
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  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠, 兔

宿主

  • 100
  • 22
  • 9
  • 2

克隆类型

  • 112
  • 21
多克隆

标记

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  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
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  • 3
  • 2
This Factor VIII antibody is conjugated to Cy3

应用范围

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  • 26
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  • 10
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  • 7
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  • 1
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
  • 抗原表位

    • 15
    • 15
    • 14
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 401-500

    交叉反应

    人, 小鼠, 兔, 大鼠

    预测反应

    Dog

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from rat factor VIII

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    Factor VIII (F8) (Coagulation Factor VIII (F8))

    别名

    Factor 8

    背景

    Synonyms: coagulation factor VIII, Ahf, Antihemophilic factor, Coagulation factor VIII, Coagulation factor VIII procoagulent component, Coagulation factor VIIIc, Dna segment on chromosome x unique 1253 expressed sequence, Dxs1253e, F8, F8 protein,F8c, FactorVIII, FVIII, Hema coagulation factor VIIIc procoagulent component, Hemophilia a, Hemophilia classic,

    Background: This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation, factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder. [provided by RefSeq, Jul 2008].

    分子量

    267kDa

    基因ID

    302470

    UniProt

    Q7TN96
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