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MOG 抗体 (PE-Cy7)

This anti-MOG antibody is a 兔 多克隆 antibody detecting MOG in FACS. Suitable for 人, 小鼠, 大鼠, Pig 和 豚鼠.
产品编号 ABIN668494
发货至: 中国

Quick Overview for MOG 抗体 (PE-Cy7) (ABIN668494)

抗原

See all MOG 抗体
MOG (Myelin Oligodendrocyte Glycoprotein (MOG))

适用

  • 78
  • 52
  • 47
  • 4
  • 4
  • 2
  • 2
  • 2
人, 小鼠, 大鼠, Pig, 豚鼠

宿主

  • 93
  • 16
  • 1
  • 1
  • 1

克隆类型

  • 84
  • 27
  • 1
多克隆

标记

  • 54
  • 18
  • 12
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This MOG antibody is conjugated to PE-Cy7

应用范围

  • 81
  • 50
  • 34
  • 22
  • 21
  • 15
  • 12
  • 11
  • 5
  • 4
  • 3
  • 1
  • 1
  • 1
Flow Cytometry (FACS)
  • 特异性

    Excitation / Emission Wavelengths: 480,565,743nm/767nm

    交叉反应

    大鼠, 猪, 豚鼠

    纯化方法

    purified by Protein A

    免疫原

    KLH conjugated synthetic peptide derived from human MOG

    亚型

    IgG
  • 应用备注

    FCM(1:100-500)
    Optimal working dilution should be determined by the investigator.

    说明

    Excitation / Emission wavelength: 496,565nm / 774nm

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 µg/µL

    缓冲液

    Aqueous buffered solution containing 100 µg/mL BSA, 50 % glycerol and 0.09 % Gentamicin.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 4 °C for 12 months

    有效期

    12 months
  • 抗原

    MOG (Myelin Oligodendrocyte Glycoprotein (MOG))

    别名

    MOG

    背景

    Myelin oligodendrocyte glycoprotein (MOG) is a key CNS-specific autoantigen for primary demyelination in multiple sclerosis. Although the disease-inducing role of MOG has been established, its precise function in the CNS remains obscure. MOG is a type I integral membrane protein possessing a single extracellular Ig variable domain (Ig-V) (3, 13, 14). The amino acid sequence of MOG is highly conserved among animal species (>90%), indicative of an important biological function. MOG is specifically expressed in the CNS on the outermost lamellae of the myelin sheath as well as the cell body and processes of oligodendrocytes. The developmentally late expression of MOG correlates with the later stages of myelinogenesis, suggesting that MOG has a role in the completion, compaction, and/or maintenance of myelin, further suggesting that MOG has an adhesive function within the CNS . Consistent with MOG's possible adhesive role in the CNS, a homodimeric form of MOG has not only been observed after isolation from the CNS but has additionally been observed in situ.

    分子量

    28kDa

    基因ID

    4340
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