MOG 抗体 (PE-Cy5)
Quick Overview for MOG 抗体 (PE-Cy5) (ABIN668493)
抗原
See all MOG 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Excitation / Emission Wavelengths: 480,565,650nm/670nm
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交叉反应
- 大鼠, 猪, 豚鼠
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纯化方法
- purified by Protein A
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免疫原
- KLH conjugated synthetic peptide derived from human MOG
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亚型
- IgG
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应用备注
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FCM(1:100-500)
Optimal working dilution should be determined by the investigator. -
说明
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Excitation / Emission wavelength: 496nm / 556nm
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 µg/µL
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缓冲液
- Aqueous buffered solution containing 100 µg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 4 °C for 12 months
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有效期
- 12 months
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- MOG (Myelin Oligodendrocyte Glycoprotein (MOG))
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别名
- MOG
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背景
- Myelin oligodendrocyte glycoprotein (MOG) is a key CNS-specific autoantigen for primary demyelination in multiple sclerosis. Although the disease-inducing role of MOG has been established, its precise function in the CNS remains obscure. MOG is a type I integral membrane protein possessing a single extracellular Ig variable domain (Ig-V) (3, 13, 14). The amino acid sequence of MOG is highly conserved among animal species (>90%), indicative of an important biological function. MOG is specifically expressed in the CNS on the outermost lamellae of the myelin sheath as well as the cell body and processes of oligodendrocytes. The developmentally late expression of MOG correlates with the later stages of myelinogenesis, suggesting that MOG has a role in the completion, compaction, and/or maintenance of myelin, further suggesting that MOG has an adhesive function within the CNS . Consistent with MOG's possible adhesive role in the CNS, a homodimeric form of MOG has not only been observed after isolation from the CNS but has additionally been observed in situ.
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分子量
- 28kDa
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基因ID
- 4340
抗原
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